The paper outlines a 2-tier approach for wide-scale biomonitoring programmes. To obtain a
high level of standardization, we suggest the use of caged organisms (mussels or fish). An …

The main mechanisms involved in heavy metal cation homeostasis in marine invertebrate
cells are described. 2. Metallothioneins are probably the most important soluble compounds …

A spectrophotometric method to evaluate the concentration of metallothioneins in the tissues
of marine organisms has been developed. Metallothionein concentration was evaluated …

The cellular processes involved in metal metabolism in molluscs are reviewed, with
emphasis on the contribution of microscopy (AMG, ARG, EPMA, and SIMS) to both basic …

Tilapia zilli were exposed to the same concentration (1 mg/L) of essential (Cu, Zn) and non-
essential (Cd, Pb) metals for 10 days so that these metals would accumulate in the liver, gill …

Mussels have been extensively utilized in the past as a biological indicator of pollution in
monitoring programs. The reason for this choice is that the mussel is a sessile, filter-feeding …

The concentration and distribution of metals in molluscan tissues, as in any other organism,
is highly dependent on the biochemical processes of metal metabolism occurring within …

Metallothionein (MT) is a sulfhydryl-rich protein involved mainly in heavy metal homeostasis
and detoxification. In this study, the use of the mussel as an experimental model allowed us …

The glutathione metabolism contains crucial antioxidant molecules to defend the organisms
against oxidants. Thus, the aim of this study was to investigate the response of the …

The biochemical features of metallothioneins and their functional role in the cell are
described. On this basis, the potential role of MTs as a biomarker of exposure in aquatic …