Lipid droplets: packing hydrophobic molecules within the aqueous cytoplasm

A Guzha, P Whitehead, T Ischebeck… - Annual review of …, 2023 - annualreviews.org
Lipid droplets, also known as oil bodies or lipid bodies, are plant organelles that
compartmentalize neutral lipids as a hydrophobic matrix covered by proteins embedded in a …

[HTML][HTML] Acyl-CoA: diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control

G Chen, JL Harwood, MJ Lemieux, SJ Stone… - Progress in Lipid …, 2022 - Elsevier
Acyl-CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the last reaction in
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …

The renaissance and enlightenment of Marchantia as a model system

JL Bowman, M Arteaga-Vazquez, F Berger… - The Plant …, 2022 - academic.oup.com
The liverwort Marchantia polymorpha has been utilized as a model for biological studies
since the 18th century. In the past few decades, there has been a Renaissance in its …

The ubiquitin-protein ligase MIEL1 localizes to peroxisomes to promote seedling oleosin degradation and lipid droplet mobilization

MS Traver, B Bartel - … of the National Academy of Sciences, 2023 - National Acad Sciences
Lipid droplets are organelles conserved across eukaryotes that store and release neutral
lipids to regulate energy homeostasis. In oilseed plants, fats stored in seed lipid droplets …

Engineering sub-organelles of a diploid Saccharomyces cerevisiae to enhance the production of 7-dehydrocholesterol

K Bi, W Wang, D Tang, Z Shi, S Tian, L Huang… - Metabolic …, 2024 - Elsevier
Dehydrocholesterol (7-DHC) is widely present in various organisms and is an important
precursor of vitamin D 3. Despite significant improvements in the biosynthesis of 7-DHC, it …

Molecular mechanisms of perilipin protein function in lipid droplet metabolism

E Griseti, AA Bello, E Bieth, B Sabbagh… - FEBS …, 2024 - Wiley Online Library
Perilipins are abundant lipid droplet (LD) proteins present in all metazoans and also in
Amoebozoa and fungi. Humans express five perilipins, which share a similar domain …

Lipid metabolism in glioblastoma: from de novo synthesis to storage

Y Kou, F Geng, D Guo - Biomedicines, 2022 - mdpi.com
Glioblastoma (GBM) is the most lethal primary brain tumor. With limited therapeutic options,
novel therapies are desperately needed. Recent studies have shown that GBM acquires …

A glossary of plant cell structures: current insights and future questions

BH Kang, CT Anderson, S Arimura, E Bayer… - The Plant …, 2022 - academic.oup.com
In this glossary of plant cell structures, we asked experts to summarize a present-day view of
plant organelles and structures, including a discussion of outstanding questions. In the …

Ties between stress and lipid droplets pre-date seeds

J de Vries, T Ischebeck - Trends in Plant Science, 2020 - cell.com
Seeds were a key evolutionary innovation. These durable structures provide a concerted
solution to two challenges on land: dispersal and stress. Lipid droplets (LDs) that act as …

Variety of plant oils: Species-specific lipid biosynthesis

AC Clews, BA Ulch, M Jesionowska… - Plant and Cell …, 2024 - academic.oup.com
Plant oils represent a large group of neutral lipids with important applications in food, feed
and oleochemical industries. Most plants accumulate oils in the form of triacylglycerol within …