Syndromes of thrombotic microangiopathy
JN George, CM Nester - New England Journal of Medicine, 2014 - Mass Medical Soc
Syndromes of Thrombotic Microangiopathy | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …
content The New England Journal of Medicine homepage Advanced Search SEARCH …
Sex as a biological variable in atherosclerosis
Atherosclerosis is a chronic inflammatory vascular disease and the predominant cause of
heart attack and ischemic stroke. Despite the well-known sexual dimorphism in the …
heart attack and ischemic stroke. Despite the well-known sexual dimorphism in the …
Molecular biology of atherosclerosis
PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
Thromboinflammation: from atherosclerosis to COVID-19
DD Wagner, LA Heger - Arteriosclerosis, thrombosis, and vascular …, 2022 - Am Heart Assoc
The activating interplay of thrombosis and inflammation (thromboinflammation) has been
established as a major underlying pathway, driving not only cardiovascular disease but also …
established as a major underlying pathway, driving not only cardiovascular disease but also …
Inflammation, von Willebrand factor, and ADAMTS13
Increasing evidence indicates that inflammation can cause thrombosis by a von Willebrand
factor (VWF)-mediated mechanism that includes endothelial activation, secretion of VWF …
factor (VWF)-mediated mechanism that includes endothelial activation, secretion of VWF …
[HTML][HTML] von Willebrand factor and inflammation
C Kawecki, PJ Lenting, CV Denis - Journal of Thrombosis and Haemostasis, 2017 - Elsevier
Von Willebrand factor (VWF) is a plasma glycoprotein best known for its crucial hemostatic
role in serving as a molecular bridge linking platelets to subendothelial components …
role in serving as a molecular bridge linking platelets to subendothelial components …
ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura
XL Zheng - Annual review of medicine, 2015 - annualreviews.org
Pathogenesis of thrombotic thrombocytopenic purpura (TTP) was a mystery for over half a
century until the discovery of ADAMTS13. ADAMTS13 is primarily synthesized in the liver …
century until the discovery of ADAMTS13. ADAMTS13 is primarily synthesized in the liver …
VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice
Innate immune cells play a major role in the early response to myocardial
ischemia/reperfusion (MI/R) injury. Recombinant human ADAMTS13 (rhADAMTS13) …
ischemia/reperfusion (MI/R) injury. Recombinant human ADAMTS13 (rhADAMTS13) …
[HTML][HTML] von Willebrand factor: the old, the new and the unknown
PJ Lenting, C Casari, OD Christophe… - Journal of thrombosis and …, 2012 - Elsevier
Summary von Willebrand factor (VWF) is a protein best known from its critical role in
hemostasis. Indeed, any dysfunction of VWF is associated with a severe bleeding tendency …
hemostasis. Indeed, any dysfunction of VWF is associated with a severe bleeding tendency …
von Willebrand factor and platelet glycoprotein Ib: a thromboinflammatory axis in stroke
F Denorme, K Vanhoorelbeke… - Frontiers in …, 2019 - frontiersin.org
von Willebrand factor (VWF) and platelets are key mediators of normal hemostasis. At sites
of vascular injury, VWF recruits platelets via binding to the platelet receptor glycoprotein Ibα …
of vascular injury, VWF recruits platelets via binding to the platelet receptor glycoprotein Ibα …