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Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …
dye with high structural tailorability is of great significance in the field of detection …
Hemicyanine‐based near‐infrared activatable probes for imaging and diagnosis of diseases
Molecular activatable probes with near‐infrared (NIR) fluorescence play a critical role in in
vivo imaging of biomarkers for drug screening and disease diagnosis. With structural …
vivo imaging of biomarkers for drug screening and disease diagnosis. With structural …
Fluorescent small organic probes for biosensing
Small-molecule based fluorescent probes are increasingly important for the detection and
imaging of biological signaling molecules due to their simplicity, high selectivity and …
imaging of biological signaling molecules due to their simplicity, high selectivity and …
Activity‐based NIR enzyme fluorescent probes for the diagnosis of tumors and image‐guided surgery
H Li, D Kim, Q Yao, H Ge, J Chung, J Fan… - Angewandte …, 2021 - Wiley Online Library
Near‐infrared (NIR) activatable fluorescent probes have been considered to be the effective
edge tools for the investigation of cell biology and disease diagnosis because of their …
edge tools for the investigation of cell biology and disease diagnosis because of their …
Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging
HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …
the location and expression levels of these enzymes in live cancer cells have considerable …
Fluorogenic probes for disease-relevant enzymes
Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …
Recognition moieties of small molecular fluorescent probes for bioimaging of enzymes
Conspectus Enzymes are a class of important substances for life, and their abnormal levels
are associated with many diseases. Thus, great progress has been made in the past decade …
are associated with many diseases. Thus, great progress has been made in the past decade …
Super-resolution imaging of mitochondrial HClO during cell ferroptosis using a near-infrared fluorescent probe
Ferroptosis is of great importance in physiological and pathological processes, which is
associated with various inflammation-related diseases, cardiovascular diseases, and even …
associated with various inflammation-related diseases, cardiovascular diseases, and even …
Recent advances in self-immolative linkers and their applications in polymeric reporting systems
AG Gavriel, MR Sambrook, AT Russell, W Hayes - Polymer Chemistry, 2022 - pubs.rsc.org
Interest in self-immolative chemistry has grown over the past decade with more research
groups harnessing the versatility to control the release of a compound from a larger …
groups harnessing the versatility to control the release of a compound from a larger …
Recent advances in the design and discovery of synthetic tyrosinase inhibitors
J Li, L Feng, L Liu, F Wang, L Ouyang, L Zhang… - European journal of …, 2021 - Elsevier
Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …