Recent developments in membrane targeting antifungal agents to mitigate antifungal resistance

D Mehta, V Saini, A Bajaj - RSC Medicinal Chemistry, 2023 - pubs.rsc.org
Fungal infections cause severe and life-threatening complications especially in
immunocompromised individuals. Antifungals targeting cellular machinery and cell …

Hydrophobicity of Cholic acid-derived amphiphiles dictates the antimicrobial specificity

S Gupta, A Arora, V Saini, D Mehta… - ACS Biomaterials …, 2022 - ACS Publications
The unique structural components of cell membranes of Gram-positive bacteria, Gram-
negative bacteria, and mycobacteria provide an excellent therapeutic target for develo** …

N-methyl Benzimidazole Tethered Cholic Acid Amphiphiles Can Eradicate S. aureus-Mediated Biofilms and Wound Infections

H Kakkar, N Chaudhary, D Mehta, V Saini… - Molecules, 2022 - mdpi.com
Infections associated with Gram-positive bacteria like S. aureus pose a major threat as these
bacteria can develop resistance and thereby limit the applications of antibiotics. Therefore …