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mRNA-based cancer therapeutics
Due to the fact that mRNA technology allows the production of diverse vaccines and
treatments in a shorter time frame and with reduced expense compared to conventional …
treatments in a shorter time frame and with reduced expense compared to conventional …
The landscape of mRNA nanomedicine
Messenger RNA (mRNA) is an emerging class of therapeutic agent for the prevention and
treatment of a wide range of diseases. The recent success of the two highly efficacious …
treatment of a wide range of diseases. The recent success of the two highly efficacious …
Lipid nanoparticle (LNP) enables mRNA delivery for cancer therapy
Messenger RNA (mRNA) has received great attention in the prevention and treatment of
various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA …
various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA …
mRNA-based therapeutics: powerful and versatile tools to combat diseases
S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …
range of incurable diseases. Recent rapid advances in biotechnology and molecular …
mRNA vaccines in disease prevention and treatment
G Zhang, T Tang, Y Chen, X Huang… - Signal transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …
treatment of diseases, thanks largely although not totally to their extraordinary performance …
The clinical progress of mRNA vaccines and immunotherapies
The emergency use authorizations (EUAs) of two mRNA-based severe acute respiratory
syndrome coronavirus (SARS-CoV)-2 vaccines approximately 11 months after publication of …
syndrome coronavirus (SARS-CoV)-2 vaccines approximately 11 months after publication of …
Emerging non-viral vectors for gene delivery
C Wang, C Pan, H Yong, F Wang, T Bo, Y Zhao… - Journal of …, 2023 - Springer
Gene therapy holds great promise for treating a multitude of inherited and acquired diseases
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …
Advances in COVID-19 mRNA vaccine development
E Fang, X Liu, M Li, Z Zhang, L Song, B Zhu… - Signal transduction and …, 2022 - nature.com
To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy
Y You, Y Tian, Z Yang, J Shi, KJ Kwak, Y Tong… - Nature biomedical …, 2023 - nature.com
The success of messenger RNA therapeutics largely depends on the availability of delivery
systems that enable the safe, effective and stable translation of genetic material into …
systems that enable the safe, effective and stable translation of genetic material into …
Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis
Safe and efficacious systemic delivery of messenger RNA (mRNA) to specific organs and
cells in vivo remains the major challenge in the development of mRNA-based therapeutics …
cells in vivo remains the major challenge in the development of mRNA-based therapeutics …