Renin-angiotensin-aldosterone (RAAS): The ubiquitous system for homeostasis and pathologies

S Patel, A Rauf, H Khan, T Abu-Izneid - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Renin-angiotensin-aldosterone system (RAAS) is a vital system of human body, as it
maintains plasma sodium concentration, arterial blood pressure and extracellular volume …

An assessment on impact of COVID-19 infection in a gender specific manner

H Agrawal, N Das, S Nathani, S Saha, S Saini… - Stem cell reviews and …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by novel coronavirus Severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It was first time reported in …

Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease: Association of British Clinical Diabetologists …

D Banerjee, P Winocour, TA Chowdhury, P De… - BMC nephrology, 2022 - Springer
People with type 1 and type 2 diabetes are at risk of develo** progressive chronic kidney
disease (CKD) and end-stage kidney failure. Hypertension is a major, reversible risk factor …

[HTML][HTML] The association of ACE1, ACE2, TMPRSS2, IFITM3 and VDR polymorphisms with COVID-19 severity: A systematic review and meta-analysis

Z Dobrijevic, D Robajac, N Gligorijevic, M Šunderic… - EXCLI …, 2022 - ncbi.nlm.nih.gov
Genes involved in the regulation of viral recognition and its entry into a host cell have been
identified as candidates for genetic association studies on COVID-19 severity. Published …

Renin‐angiotensin‐aldosterone system, glucose metabolism and incident type 2 diabetes mellitus: MESA

JJ Joseph, JB Echouffo Tcheugui, VS Effoe… - Journal of the …, 2018 - Am Heart Assoc
Background Mechanistic studies suggest that aldosterone impairs glucose metabolism. We
investigated the cross‐sectional associations of aldosterone and plasma renin activity with …

Inflammation: the link between neural and vascular impairment in the diabetic retina and therapeutic implications

H Ramos, C Hernández, R Simó… - International Journal of …, 2023 - mdpi.com
The etiology of diabetic retinopathy (DR) is complex, multifactorial and compromises all the
elements of the retinal neurovascular unit (NVU). This diabetic complication has a chronic …

The crosstalk among TLR2, TLR4 and pathogenic pathways; a treasure trove for treatment of diabetic neuropathy

SH Aghamiri, K Komlakh, M Ghaffari - Inflammopharmacology, 2022 - Springer
Diabetes is correlated with organ failures as a consequence of microvascular diabetic
complications, including neuropathy, nephropathy, and retinopathy. These difficulties come …

The role of inflammation and neurodegeneration in diabetic macular edema

V Starace, M Battista, M Brambati… - Therapeutic …, 2021 - journals.sagepub.com
The pathogenesis of diabetic macular edema (DME) is complex. Persistently high blood
glucose activates multiple cellular pathways and induces inflammation, oxidation stress, and …

[HTML][HTML] Pregnancy, preeclampsia, and covid-19: susceptibility and mechanisms: A Review Study

B Sayad, ZM Afshar, F Mansouri, M Salimi… - … journal of fertility & …, 2022 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters cells through
angiotensin converting enzyme 2 (ACE2), which expression of its gene increases during …

Update on genetics and diabetic retinopathy

BM Hampton, SG Schwartz, MA Brantley Jr… - Clinical …, 2015 - Taylor & Francis
Clinical risk factors for diabetic retinopathy (DR), such as duration of disease and degree of
glucose control, do not adequately predict disease progression in individual patients …