Age-related macular degeneration (AMD) is a leading cause of blindness in aged
individuals. Recent advances have highlighted the essential role of immune processes in …

PURPOSE: To fax: 404-778-5089; review clinicopathologic findings of choroidal
neovascularization (CNV) in a historical framework with emphasis on pathobiology and …

PURPOSE: To determine the cellular origin and the vascular endothelial growth factor
(VEGF) immunoreactivity of the nonvascular stromal cells in surgically excised age-related …

Background: Delineation qf the morphologic aspects of age-related macular degeneration
(ARMD) is helpful in correlation with the clinical features and may contribute to …

The Notch signaling pathway regulates developmental cell-fate decisions and has recently
also been linked to inflammatory diseases. Although therapies targeting Notch signaling in …

AIMS/BACKGROUND The late stages of age-related maculopathy (ARM), especially
neovascular macular degeneration (ARMD), can severely affect central vision and are the …

Purpose: To determine the expression of angiogenic cytokines in macrophages and retinal
pigment epithelium cells in choroidal neovascularization (CNV). Methods: Ten surgically …

Aetiological and immunological aspects of AMD, a leading cause of blindness in Western
countries, have been reviewed. Developmental studies suggest that anatomical features …

purpose. To investigate the distribution of inflammatory mediators such as interleukin (IL)-1β
and tumor necrosis factor (TNF)-α and angiogenic cytokines such as vascular endothelial …

Age related macular degeneration (AMD) is a complex multifactorial disease caused by the
interplay of age and genetic and environmental risk factors. A common feature observed in …