Intranasal COVID-19 vaccines: From bench to bed
A Alu, L Chen, H Lei, Y Wei, X Tian, X Wei - EBioMedicine, 2022 - thelancet.com
Currently licensed COVID-19 vaccines are all designed for intramuscular (IM) immunization.
However, vaccination today failed to prevent the virus infection through the upper respiratory …
However, vaccination today failed to prevent the virus infection through the upper respiratory …
Mesoporous silica nanoparticles for pulmonary drug delivery
A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …
the leading causes of death in the world due to the lack of effective lung therapies, mainly …
Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases
S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
[HTML][HTML] Traditional Chinese medicine combined with pulmonary drug delivery system and idiopathic pulmonary fibrosis: rationale and therapeutic potential
Y Zhang, P Lu, H Qin, Y Zhang, X Sun, X Song… - Biomedicine & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary interstitial inflammatory
disease of unknown etiology, and is also a sequela in severe patients with the Coronavirus …
disease of unknown etiology, and is also a sequela in severe patients with the Coronavirus …
A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases
Pulmonary drug delivery is a highly attractive topic for the treatment of infectious lung
diseases. Drug delivery via the pulmonary route offers unique advantages of no first-pass …
diseases. Drug delivery via the pulmonary route offers unique advantages of no first-pass …
Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells—overview and perspectives
X Cao, JP Coyle, R **ong, Y Wang, RH Heflich… - In Vitro Cellular & …, 2021 - Springer
The lung is an organ that is directly exposed to the external environment. Given the large
surface area and extensive ventilation of the lung, it is prone to exposure to airborne …
surface area and extensive ventilation of the lung, it is prone to exposure to airborne …
PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases
X Guo, X Zuo, Z Zhou, Y Gu, H Zheng, X Wang… - International Journal of …, 2023 - mdpi.com
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …
are critical areas of medical research, as millions of people are affected worldwide. In fact …
Are inhaled mRNA vaccines safe and effective? A review of preclinical studies
Introduction Injected mRNA vaccines have been proven effective and safe in the SARS-CoV-
2 pandemic. Using the machinery of the cell, mRNA vaccines translate into an antigen …
2 pandemic. Using the machinery of the cell, mRNA vaccines translate into an antigen …
[HTML][HTML] Nebulised delivery of RNA formulations to the lungs: From aerosol to cytosol
MT Neary, LM Mulder, PS Kowalski… - Journal of Controlled …, 2024 - Elsevier
In the past decade RNA-based therapies such as small interfering RNA (siRNA) and
messenger RNA (mRNA) have emerged as new and ground-breaking therapeutic agents for …
messenger RNA (mRNA) have emerged as new and ground-breaking therapeutic agents for …
Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease
M Cazzola, F Cavalli, OS Usmani… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Proper device selection is crucial for the clinical results of inhalation therapy.
However, none of the available devices fully conforms to the requirements for delivering …
However, none of the available devices fully conforms to the requirements for delivering …