Study on hydrodynamics characteristics in a gas-liquid stirred tank with a self-similarity impeller based on CFD-PBM coupled model

D Gu, L Wen, H Xu, M Ye - Journal of the Taiwan Institute of Chemical …, 2023 - Elsevier
Background In general, radial impeller has been the most widely employed for the gas-liquid
mixing process in the stirred tank. However, gas cavities are easy to form behind the …

Beyond heuristics: CFD‐based novel multiparameter scale‐up for geometrically disparate bioreactors demonstrated at industrial 2kL–10kL scales

J Scully, LB Considine, MT Smith… - Biotechnology and …, 2020 - Wiley Online Library
The timely delivery of the most up‐to‐date medicines and drug products is essential for
patients throughout the world. Successful scaling of the bioreactors used within the …

Effects of impeller types on gas-liquid mixing and oxygen mass transfer in aerated stirred reactors

D Li, W Chen - Process Safety and Environmental Protection, 2022 - Elsevier
Aeration and stir are vital steps in wastewater treatment plants (WWTPs) to enhance
dissolved oxygen (DO) concentration in water. In laboratories, aerated stirred reactors …

Online monitoring of the respiratory quotient reveals metabolic phases during microaerobic 2,3‐butanediol production with Bacillus licheniformis

B Heyman, H Tulke, SP Putri… - Engineering in life …, 2020 - Wiley Online Library
Microaerobic cultivation conditions are often beneficial for the biotechnological production of
reduced metabolites like 2, 3‐butanediol. However, due to oxygen limitation, process …

Power number and hydrodynamic characterization of a stirred vessel equipped with a retreat-blade impeller and different types of pharmaceutical single baffles

C Sirasitthichoke, S Salloum, PM Armenante - Chemical Engineering …, 2022 - Elsevier
Many operations conducted in the pharmaceutical industry take place in glass-lined vessels
provided with a Retreat-Blade Impeller (RBI) and one of different types of single baffles. Little …

Bubble size distribution in aerated stirred tanks: Quantifying the effect of impeller-stator design

D Mesa, PR Brito-Parada - Chemical Engineering Research and Design, 2020 - Elsevier
Bubble size is an important variable in aerated stirred tanks as it determines the surface
area available for reactions. In the bubble break-up process, impellers play a key role …

Process optimization in a stirred tank bioreactor based on CFD-Taguchi method: A case study

L Shu, M Yang, H Zhao, T Li, L Yang, X Zou… - Journal of Cleaner …, 2019 - Elsevier
Cleaner aerobic fermentation with high efficiency is of great significance to microbial
production. In an aerobic fermentation process, gas holdup and power consumption are …

Axial distributions of bubble–liquid mass transfer coefficient in laboratory-scale stirred tank with viscous Newtonian and non-Newtonian fluids

H Ali, J Solsvik - Physics of Fluids, 2020 - pubs.aip.org
Splitting of the volumetric mass transfer coefficient into a bubble–liquid mass transfer
coefficient and interfacial area is essential to quantify the mass transfer rate of stirred tanks …

[HTML][HTML] A quasi-analytical prediction method for gear load-independent power losses for shroud approaching

X Zhu, JN Bian, Y Dai - … Science and Technology, an International Journal, 2023 - Elsevier
To limit the adverse effect of the fluid pressure field in high-speed gearing systems,
especially for the main reducer of helicopters, shrouds usually adopted to enclose and …

Chaotic mixing and mass transfer characteristics of fractal impellers in gas-liquid stirred tank

D Gu, Y Mei, L Wen, X Wang, Z Liu - Journal of the Taiwan Institute of …, 2021 - Elsevier
Gas-liquid mixing characteristics in fractal impeller stirred tank were experimentally
investigated by measuring multi-scale entropy (MSE), relative power demand (RPD), local …