Vascular cognitive impairment and dementia (VCID) is a major heterogeneous brain
disease caused by multiple factors, and it is the second most common type of dementia in …

Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …

Neuronal computation is energetically expensive. Consequently, the brain's limited energy
supply imposes constraints on its information processing capability. Most brain energy is …

Functional brain imaging with positron emission tomography and magnetic resonance
imaging has been used extensively to map regional changes in brain activity. The signal …

In vivo monitoring of animal physiological information plays a crucial role in promptly alerting
humans to potential diseases in animals and aiding in the exploration of mechanisms …

Neural activity has been suggested to initially trigger ATP production by glycolysis, rather
than oxidative phosphorylation, for three reasons: glycolytic enzymes are associated with …

Neuronal activity is a high‐energy demanding process recruiting all neural cells that adapt
their metabolism to sustain the energy and redox balance of neurons. During …

The brain is a heterogeneous organ with regionally varied and constantly changing
energetic needs. Blood vessels in the brain are equipped with control mechanisms that …

It has become accepted in the neuroscience community that perception and performance
are quintessentially multisensory by nature. Using the full palette of modern brain imaging …

The hallmark clinical symptom of early Alzheimer's disease (AD) is episodic memory
impairment. Recent functional imaging studies suggest that memory function is subserved …