Common causes of hearing loss in humans-exposure to loud noise or ototoxic drugs and
aging-often damage sensory hair cells, reflected as elevated thresholds on the clinical …

Understanding the biology of the previously underappreciated sensitivity of cochlear
synapses to noise insult, and its clinical consequences, is becoming a mission for a growing …

Objectives: Recent animal studies demonstrated that cochlear synaptopathy, a partial loss of
inner hair cell-auditory nerve fiber synapses, can occur in response to noise exposure …

When exposed to continuous high-level noise, cochlear neurons are more susceptible to
damage than hair cells (HCs): exposures causing temporary threshold shifts (TTS) without …

Rats make excellent models for the study of medical, biological, genetic, and behavioral
phenomena given their adaptability, robustness, survivability, and intelligence. The rat's …

Otologic Outcomes After Blast Injury: The Boston Marathon Ex... : Otology & Neurotology
Otologic Outcomes After Blast Injury: The Boston Marathon Experience : Otology & …

Hypotonic stress causes the activation of swelling-activated nonselective cation channels
(NSCCs), which leads to Ca 2+-dependent regulatory volume decrease (RVD) and adaptive …

Although most trauma centers have experience with the imaging and management of
gunshot wounds, in most regions blast wounds such as the ones encountered in terrorist …

The tonotopic map of the mammalian cochlea is commonly thought to be determined by the
passive mechanical properties of the basilar membrane. The other tissues and cells that …

There is indirect evidence that the mammalian cochlea in the low-frequency apical and the
more commonly studied high-frequency basal regions function in fundamentally different …