Multicomponent reactions (MCRs) have proved as a valuable tool for organic and medicinal
chemist because of their ability to introduce a large degree of chemical diversity in the …

Isocyanides as key intermediates and magic reactants have been widely applied in organic
reactions for direct access to a broad spectrum of remarkable organic compounds. Although …

Lactams are very important heterocycles as a result of their presence in a wide range of
bioactive molecules, natural products and drugs, and also due their utility as versatile …

A diversity-oriented access to diastereoselective arylidene 2, 5-diketopiperazines is
elaborated via a sequential Ugi post-transformation involving catalytic cyclization and …

An efficient approach for the synthesis of pyranoquinolines through the indium-catalyzed
activation of alkynes is reported. Intramolecular hydroamidation of alkynes can proceed …

Nowadays, among synthetic organic chemists, the Ugi four-component reaction (U-4CR), is
known as the most important and useful isocyanide-based multicomponent reactions …

A convenient method for selective synthesis of ethyl 1-aryl-5-formyl-1 H-1, 2, 3-triazole-4-
carboxylates and 1-aryl-1, 5-dihydro-4 H-[1, 2, 3]-triazolo [4, 5-d] pyridazin-4-ones has been …

A ZnCl 2-catalyzed regio-and diastereoselective one-pot sequential Knoevenagel
condensation/1, 3-dipolar cycloaddition reaction of CH acids (oxindole, 1, 3-indandione, and …

Facile and efficient NaOH-promoted one-pot regioselective synthesis of 5, 7-dimethyl-3-
(arylamino) isoxazolo [5, 4-d] pyrimidine-4, 6 (5 H, 7 H)-diones and 5, 7-dimethyl-3 …

A simple and efficient synthetic route to the novel 3a, 4-dihydro-3 H, 7 H-and 4 H, 7 H-
pyrazolo [4′, 3′: 5, 6] pyrano [4, 3-c][1, 2] oxazole ring systems from 3-(prop-2-en-1-yloxy) …