The physiology and genetics of bacterial responses to antibiotic combinations
Several promising strategies based on combining or cycling different antibiotics have been
proposed to increase efficacy and counteract resistance evolution, but we still lack a deep …
proposed to increase efficacy and counteract resistance evolution, but we still lack a deep …
Size and charge effects of metal nanoclusters on antibacterial mechanisms
HT Draviana, I Fitriannisa, M Khafid… - Journal of …, 2023 - Springer
Nanomaterials, specifically metal nanoclusters (NCs), are gaining attention as a promising
class of antibacterial agents. Metal NCs exhibit antibacterial properties due to their …
class of antibacterial agents. Metal NCs exhibit antibacterial properties due to their …
Engineering Platelet Membrane‐Coated Bimetallic MOFs as Biodegradable Nanozymes for Efficient Antibacterial Therapy
Q Shi, Y Zhao, M Liu, F Shi, L Chen, X Xu, J Gao… - Small, 2024 - Wiley Online Library
Nanocatalytic‐based wound therapeutics present a promising strategy for generating
reactive oxygen species (ROS) to antipathogen to promote wound healing. However, the full …
reactive oxygen species (ROS) to antipathogen to promote wound healing. However, the full …
Unrealized targets in the discovery of antibiotics for gram-negative bacterial infections
U Theuretzbacher, B Blasco, M Duffey… - Nature Reviews Drug …, 2023 - nature.com
Advances in areas that include genomics, systems biology, protein structure determination
and artificial intelligence provide new opportunities for target-based antibacterial drug …
and artificial intelligence provide new opportunities for target-based antibacterial drug …
Surveying membrane landscapes: a new look at the bacterial cell surface
Recent studies applying advanced imaging techniques are changing the way we
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …
[書籍][B] An introduction to medicinal chemistry
GL Patrick - 2023 - books.google.com
Providing an introduction to medicinal chemistry, this resource covers basic principles and
background, and describes the general tactics and strategies involved in develo** an …
background, and describes the general tactics and strategies involved in develo** an …
Outer membrane porins contribute to antimicrobial resistance in gram-negative bacteria
G Zhou, Q Wang, Y Wang, X Wen, H Peng, R Peng… - Microorganisms, 2023 - mdpi.com
Gram-negative bacteria depend on their cell membranes for survival and environmental
adaptation. They contain two membranes, one of which is the outer membrane (OM), which …
adaptation. They contain two membranes, one of which is the outer membrane (OM), which …
Third-generation tetracyclines: current knowledge and therapeutic potential
D Kounatidis, M Dalamaga, E Grivakou, I Karampela… - Biomolecules, 2024 - mdpi.com
Tetracyclines constitute a unique class of antibiotic agents, widely prescribed for both
community and hospital infections due to their broad spectrum of activity. Acting by …
community and hospital infections due to their broad spectrum of activity. Acting by …
Degradable hydrogel adhesives with enhanced tissue adhesion, superior self‐healing, cytocompatibility, and antibacterial property
Y Yang, K Shi, K Yu, F **ng, H Lai… - Advanced Healthcare …, 2022 - Wiley Online Library
Degradable hydrogel adhesives with multifunctional advantages are promising to be
candidates as hemostatic agents, surgical sutures, and wound dressings. In this study …
candidates as hemostatic agents, surgical sutures, and wound dressings. In this study …
Targeting bacterial outer-membrane remodelling to impact antimicrobial drug resistance
The cell envelope is essential for survival and adaptation of bacteria. Bacterial membrane
proteins include the major porins that mediate the influx of nutrients and several classes of …
proteins include the major porins that mediate the influx of nutrients and several classes of …