Tumor penetrating peptides for improved drug delivery

E Ruoslahti - Advanced drug delivery reviews, 2017 - Elsevier
In vivo screening of phage libraries in tumor-bearing mice has been used to identify
peptides that direct phage homing to a tumor. The power of in vivo phage screening is …

Anticancer peptides mechanisms, simple and complex

P Norouzi, M Mirmohammadi, MHH Tehrani - Chemico-Biological …, 2022 - Elsevier
Peptide therapy has started since 1920s with the advent of insulin application, and now it
has emerged as a new approach in treatment of diseases including cancer. Using anti …

Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer

X Liu, P Lin, I Perrett, J Lin, YP Liao… - The Journal of …, 2017 - Am Soc Clin Investig
Pancreatic ductal adenocarcinoma (PDAC) is almost uniformly fatal; however, some
improvement in overall survival has been achieved with the introduction of nanocarriers that …

Tumor‐homing peptide and its utility for advanced cancer medicine

E Kondo, H Iioka, K Saito - Cancer Science, 2021 - Wiley Online Library
Cell‐penetrating peptides, such as antibodies, have gained great attention as tools for the
development of specific delivery systems for payloads, which might be applied as non …

Strategies for delivering nanoparticles across tumor blood vessels

V Sheth, L Wang, R Bhattacharya… - Advanced functional …, 2021 - Wiley Online Library
Nanoparticle transport across tumor blood vessels is a key step in nanoparticle delivery to
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …

Recent progress in biomedical applications of RGD‐based ligand: from precise cancer theranostics to biomaterial engineering: a systematic review

M Alipour, M Baneshi, S Hosseinkhani… - … Research Part A, 2020 - Wiley Online Library
Arginine‐glycine‐aspartic acid (RGD) peptide family is known as the most prominent ligand
for extracellular domain of integrin receptors. Specific expression of these receptors in …

Size shrinkable drug delivery nanosystems and priming the tumor microenvironment for deep intratumoral penetration of nanoparticles

Y Niu, J Zhu, Y Li, H Shi, Y Gong, R Li, Q Huo… - Journal of Controlled …, 2018 - Elsevier
The penetration of nanomedicine into solid tumor still constitutes a great challenge for
cancer therapy, which lead to the failure of thorough clearance of tumor cells. Aiming at …

Hyaluronic acid-based nano drug delivery systems for breast cancer treatment: Recent advances

Y Jia, S Chen, C Wang, T Sun, L Yang - Frontiers in bioengineering …, 2022 - frontiersin.org
Breast cancer (BC) is the most common malignancy among females worldwide, and high
resistance to drugs and metastasis rates are the leading causes of death in BC patients …

Tumor target amplification: Implications for nano drug delivery systems

K Seidi, HA Neubauer, R Moriggl… - Journal of controlled …, 2018 - Elsevier
Tumor cells overexpress surface markers which are absent from normal cells. These tumor-
restricted antigenic signatures are a fundamental basis for distinguishing on-target from off …