Prostate cancer cells are exquisitely dependent on androgen receptor (AR) activity for
proliferation and survival. As these functions are critical targets of therapeutic intervention for …

Abstract Purpose: Hypermethylation of the CpG island at the promoter region of the π-class
glutathione S-transferase gene (GSTP1) is the most common somatic genome abnormality …

Background Tissue biomarkers could pivotally improve clinical outcome prediction following
prostate cancer therapy. Clinically, prostate cancer is managed by diverse treatment …

We evaluated whether low‐dosed interferon alpha (IFNa) may augment the anti‐tumor
potential of the histone deacetylase (HDAC)‐inhibitor valproic acid (VPA) on prostate cancer …

Background: Prostate cancer is the second most common male cancer and remains a
leading cause of cancer death worldwide. Heterogeneity regarding recurrence, tumor …

The genetic alterations leading to prostate cancer are gradually being discovered. A wide
variety of genes have been associated with prostate cancer development as well as tumor …

Prostate cancer is the most common malignancy among American men and is the second-
leading cause of cancer-related mortality. Although radical prostatectomy and radiation …

Background Loss of normal cell cycle control is an early event in the evolution of cancer. The
expression of cyclin-dependent kinase (CDK) inhibitors p16 and p27 has been previously …

En este trabajo de revisión se exponen los criterios diagnósticos de cáncer en la biopsia
prostática así como el significado de otras lesiones morfológicas (PIN de alto grado …

Background The Tumor Node Metastasis (TNM) stage cannot accurately predict the
prognosis of patients in pulmonary squamous cell carcinoma (SQCC). The aim of the …