[HTML][HTML] Inflammation and stroke: an overview
J Anrather, C Iadecola - Neurotherapeutics, 2016 - Elsevier
The immune response to acute cerebral ischemia is a major factor in stroke pathobiology
and outcome. While the immune response starts locally in occluded and hypoperfused …
and outcome. While the immune response starts locally in occluded and hypoperfused …
Systemic inflammation after stroke: implications for post‐stroke comorbidities
Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …
research, and the modulation of neuroinflammatory pathways has been identified as a …
Monocyte trafficking to the brain with stress and inflammation: a novel axis of immune-to-brain communication that influences mood and behavior
HIGHLIGHTS Psychological stress activates neuroendocrine pathways that alter immune
responses. Stress-induced alterations in microglia phenotype and monocyte priming leads …
responses. Stress-induced alterations in microglia phenotype and monocyte priming leads …
The role of immune cells in post-stroke angiogenesis and neuronal remodeling: the known and the unknown
Y Ma, S Yang, Q He, D Zhang, J Chang - Frontiers in immunology, 2021 - frontiersin.org
Following a cerebral ischemic event, substantial alterations in both cellular and molecular
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …
[HTML][HTML] Stem cell therapy for abrogating stroke-induced neuroinflammation and relevant secondary cell death mechanisms
C Stonesifer, S Corey, S Ghanekar, Z Diamandis… - Progress in …, 2017 - Elsevier
Ischemic stroke is a leading cause of death worldwide. A key secondary cell death
mechanism mediating neurological damage following the initial episode of ischemic stroke …
mechanism mediating neurological damage following the initial episode of ischemic stroke …
Therapeutic targets of oxidative/nitrosative stress and neuroinflammation in ischemic stroke: Applications for natural product efficacy with omics and systemic biology
Oxidative/nitrosative stress and neuroinflammation are critical pathological processes in
cerebral ischemia-reperfusion injury, and their intimate interactions mediate neuronal …
cerebral ischemia-reperfusion injury, and their intimate interactions mediate neuronal …
Development of Spleen Targeting H2S Donor Loaded Liposome for the Effective Systemic Immunomodulation and Treatment of Inflammatory Bowel Disease
Nanoparticles are primarily taken up by immune cells after systemic administration. Thus,
they are considered an ideal drug delivery vehicle for immunomodulation. Because the …
they are considered an ideal drug delivery vehicle for immunomodulation. Because the …
Regulatory T cells in ischemic stroke
H Wang, J Ye, L Cui, S Chu, N Chen - Acta Pharmacologica Sinica, 2022 - nature.com
Recent evidence shows that when ischemic stroke (IS) occurs, the BBB would be destructed,
thereby promoting the immune cells to migrate into the brain, suggesting that the immune …
thereby promoting the immune cells to migrate into the brain, suggesting that the immune …
Re-establishment of anxiety in stress-sensitized mice is caused by monocyte trafficking from the spleen to the brain
Background Persistent anxiety-like symptoms may have an inflammatory-related
pathophysiology. Our previous work using repeated social defeat (RSD) in mice showed that …
pathophysiology. Our previous work using repeated social defeat (RSD) in mice showed that …
Systemic inflammation in hemorrhagic strokes–A novel neurological sign and therapeutic target?
Growing evidences suggest that stroke is a systemic disease affecting many organ systems
beyond the brain. Stroke-related systemic inflammatory response and immune …
beyond the brain. Stroke-related systemic inflammatory response and immune …