Imaging brain microstructure with diffusion MRI: practicality and applications

DC Alexander, TB Dyrby, M Nilsson… - NMR in …, 2019 - Wiley Online Library
This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI

DK Jones, DC Alexander, R Bowtell, M Cercignani… - NeuroImage, 2018 - Elsevier
The key component of a microstructural diffusion MRI 'super-scanner'is a dedicated high-
strength gradient system that enables stronger diffusion weightings per unit time compared …

Anatomical accuracy of brain connections derived from diffusion MRI tractography is inherently limited

C Thomas, FQ Ye, MO Irfanoglu, P Modi… - Proceedings of the …, 2014 - pnas.org
Tractography based on diffusion-weighted MRI (DWI) is widely used for map** the
structural connections of the human brain. Its accuracy is known to be limited by technical …

[HTML][HTML] Accelerated microstructure imaging via convex optimization (AMICO) from diffusion MRI data

A Daducci, EJ Canales-Rodríguez, H Zhang, TB Dyrby… - Neuroimage, 2015 - Elsevier
Microstructure imaging from diffusion magnetic resonance (MR) data represents an
invaluable tool to study non-invasively the morphology of tissues and to provide a biological …

Advances in diffusion MRI acquisition and processing in the Human Connectome Project

SN Sotiropoulos, S Jbabdi, J Xu, JL Andersson… - Neuroimage, 2013 - Elsevier
Abstract The Human Connectome Project (HCP) is a collaborative 5-year effort to map
human brain connections and their variability in healthy adults. A consortium of HCP …

Using diffusion tractography to predict cortical connection strength and distance: a quantitative comparison with tracers in the monkey

CJ Donahue, SN Sotiropoulos, S Jbabdi… - Journal of …, 2016 - jneurosci.org
Tractography based on diffusion MRI offers the promise of characterizing many aspects of
long-distance connectivity in the brain, but requires quantitative validation to assess its …

Limits to anatomical accuracy of diffusion tractography using modern approaches

KG Schilling, V Nath, C Hansen, P Parvathaneni… - Neuroimage, 2019 - Elsevier
Diffusion MRI fiber tractography is widely used to probe the structural connectivity of the
brain, with a range of applications in both clinical and basic neuroscience. Despite …

An open resource combining multi-contrast MRI and microscopy in the macaque brain

AFD Howard, IN Huszar, A Smart, M Cottaar… - Nature …, 2023 - nature.com
Understanding brain structure and function often requires combining data across different
modalities and scales to link microscale cellular structures to macroscale features of whole …

Orientationally invariant indices of axon diameter and density from diffusion MRI

DC Alexander, PL Hubbard, MG Hall, EA Moore… - Neuroimage, 2010 - Elsevier
This paper proposes and tests a technique for imaging orientationally invariant indices of
axon diameter and density in white matter using diffusion magnetic resonance imaging …

Compartment models of the diffusion MR signal in brain white matter: a taxonomy and comparison

E Panagiotaki, T Schneider, B Siow, MG Hall… - Neuroimage, 2012 - Elsevier
This paper aims to identify the minimum requirements for an accurate model of the diffusion
MR signal in white matter of the brain. We construct a taxonomy of multi-compartment …