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How does adenosine control neuronal dysfunction and neurodegeneration?
RA Cunha - Journal of neurochemistry, 2016 - Wiley Online Library
The adenosine modulation system mostly operates through inhibitory A1 (A1R) and
facilitatory A2A receptors (A2AR) in the brain. The activity‐dependent release of adenosine …
facilitatory A2A receptors (A2AR) in the brain. The activity‐dependent release of adenosine …
Are cannabidiol and Δ9‐tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review
JM McPartland, M Duncan, V Di Marzo… - British journal of …, 2015 - Wiley Online Library
Based upon evidence that the therapeutic properties of C annabis preparations are not
solely dependent upon the presence of Δ9‐tetrahydrocannabinol (THC), pharmacological …
solely dependent upon the presence of Δ9‐tetrahydrocannabinol (THC), pharmacological …
Adenosine receptors: expression, function and regulation
Adenosine receptors (ARs) comprise a group of G protein-coupled receptors (GPCR) which
mediate the physiological actions of adenosine. To date, four AR subtypes have been …
mediate the physiological actions of adenosine. To date, four AR subtypes have been …
Contribution of axonal orientation to pathway-dependent modulation of excitatory transmission by direct current stimulation in isolated rat hippocampus
Transcranial direct current stimulation (tDCS) is a method for modulating cortical excitability
by weak constant electrical current that is applied through scalp electrodes. Although often …
by weak constant electrical current that is applied through scalp electrodes. Although often …
The role of adenosine A2A receptors in Alzheimer's disease and tauopathies
A Launay, O Nebie, JV Shankara, T Lebouvier… - …, 2023 - Elsevier
Adenosine signals through four distinct G protein-coupled receptors that are located at
various synapses, cell types and brain areas. Through them, adenosine regulates …
various synapses, cell types and brain areas. Through them, adenosine regulates …
Ecto-5′-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions
Adenosine is a neuromodulator acting through inhibitory A1 receptors (A1Rs) and facilitatory
A2ARs, which have similar affinities for adenosine. It has been shown that the activity of …
A2ARs, which have similar affinities for adenosine. It has been shown that the activity of …
Purinergic signaling orchestrating neuron-glia communication
P Agostinho, D Madeira, L Dias, AP Simões… - Pharmacological …, 2020 - Elsevier
This review discusses the evidence supporting a role for ATP signaling (operated by P 2 X
and P 2 Y receptors) and adenosine signaling (mainly operated by A 1 and A 2A receptors) …
and P 2 Y receptors) and adenosine signaling (mainly operated by A 1 and A 2A receptors) …
[HTML][HTML] Striatopallidal adenosine A2A receptor modulation of goal-directed behavior: Homeostatic control with cognitive flexibility
Dysfunction of goal-directed behaviors under stressful or pathological conditions results in
impaired decision-making and loss of flexibility of thoughts and behaviors, which underlie …
impaired decision-making and loss of flexibility of thoughts and behaviors, which underlie …
Adenosine receptor neurobiology: overview
Adenosine is a naturally occurring nucleoside that is distributed ubiquitously throughout the
body as a metabolic intermediary. In the brain, adenosine functions as an important …
body as a metabolic intermediary. In the brain, adenosine functions as an important …
Cannabis: a treasure trove or pandora's box?
Background & Objective: Cannabis is one of the earliest cultivated plants. Cannabis of
industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is …
industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is …