Controlling mass and energy diffusion with metamaterials
Diffusion driven by temperature or concentration gradients is a fundamental mechanism of
energy and mass transport that inherently differs from wave propagation in both physical …
energy and mass transport that inherently differs from wave propagation in both physical …
A brief guideline for studies of phase-separated biomolecular condensates
Y Gao, X Li, P Li, Y Lin - Nature Chemical Biology, 2022 - nature.com
Cells are exquisitely compartmentalized to achieve precise spatiotemporal regulation of
myriad processes and pathways. Phase separation offers one way to achieve territorial …
myriad processes and pathways. Phase separation offers one way to achieve territorial …
Dissolution of oncofusion transcription factor condensates for cancer therapy
Cancer-associated chromosomal rearrangements can result in the expression of numerous
pathogenic fusion proteins. The mechanisms by which fusion proteins contribute to …
pathogenic fusion proteins. The mechanisms by which fusion proteins contribute to …
PICNIC accurately predicts condensate-forming proteins regardless of their structural disorder across organisms
Biomolecular condensates are membraneless organelles that can concentrate hundreds of
different proteins in cells to operate essential biological functions. However, accurate …
different proteins in cells to operate essential biological functions. However, accurate …
Specificity and competition of mRNAs dominate droplet pattern in protein phase separation
F Xu, D Miao, W Li, J **, Z Liu, C Shen, J Zhang… - Physical Review …, 2023 - APS
Phase separation is a ubiquitous and emerging mechanism underlying intracellular
organization. Yet how distinct molecular compositions in phase-separated condensates are …
organization. Yet how distinct molecular compositions in phase-separated condensates are …
Open questions on liquid–liquid phase separation
E Spruijt - Communications Chemistry, 2023 - nature.com
Liquid-liquid phase separation (LLPS) underlies the formation of intracellular membraneless
compartments in biology and may have played a role in the formation of protocells that …
compartments in biology and may have played a role in the formation of protocells that …
PhaSepDB in 2022: annotating phase separation-related proteins with droplet states, co-phase separation partners and other experimental information
Phase separation (PS) proteins form droplets to regulate myriad membraneless organelles
(MLOs) and cellular pathways such as transcription, signaling transduction and protein …
(MLOs) and cellular pathways such as transcription, signaling transduction and protein …
Achieving Environmentally‐Adaptive and Multifunctional Hydrodynamic Metamaterials through Active Control
As hydrodynamic metamaterials continue to develop, the inherent limitations of passive‐
mode metamaterials become increasingly apparent. First, passive devices are typically …
mode metamaterials become increasingly apparent. First, passive devices are typically …
Membraneless organelles in health and disease: exploring the molecular basis, physiological roles and pathological implications
Y Li, Y Liu, XY Yu, Y Xu, X Pan, Y Sun… - … and Targeted Therapy, 2024 - nature.com
Once considered unconventional cellular structures, membraneless organelles (MLOs),
cellular substructures involved in biological processes or pathways under physiological …
cellular substructures involved in biological processes or pathways under physiological …
CD-CODE: crowdsourcing condensate database and encyclopedia
The discovery of biomolecular condensates transformed our understanding of intracellular
compartmentalization of molecules. To integrate interdisciplinary scientific knowledge about …
compartmentalization of molecules. To integrate interdisciplinary scientific knowledge about …