Controlling mass and energy diffusion with metamaterials

F Yang, Z Zhang, L Xu, Z Liu, P **, P Zhuang… - Reviews of Modern …, 2024 - APS
Diffusion driven by temperature or concentration gradients is a fundamental mechanism of
energy and mass transport that inherently differs from wave propagation in both physical …

A brief guideline for studies of phase-separated biomolecular condensates

Y Gao, X Li, P Li, Y Lin - Nature Chemical Biology, 2022 - nature.com
Cells are exquisitely compartmentalized to achieve precise spatiotemporal regulation of
myriad processes and pathways. Phase separation offers one way to achieve territorial …

Dissolution of oncofusion transcription factor condensates for cancer therapy

Y Wang, C Yu, G Pei, W Jia, T Li, P Li - Nature Chemical Biology, 2023 - nature.com
Cancer-associated chromosomal rearrangements can result in the expression of numerous
pathogenic fusion proteins. The mechanisms by which fusion proteins contribute to …

PICNIC accurately predicts condensate-forming proteins regardless of their structural disorder across organisms

A Hadarovich, HR Singh, S Ghosh… - Nature …, 2024 - nature.com
Biomolecular condensates are membraneless organelles that can concentrate hundreds of
different proteins in cells to operate essential biological functions. However, accurate …

Specificity and competition of mRNAs dominate droplet pattern in protein phase separation

F Xu, D Miao, W Li, J **, Z Liu, C Shen, J Zhang… - Physical Review …, 2023 - APS
Phase separation is a ubiquitous and emerging mechanism underlying intracellular
organization. Yet how distinct molecular compositions in phase-separated condensates are …

Open questions on liquid–liquid phase separation

E Spruijt - Communications Chemistry, 2023 - nature.com
Liquid-liquid phase separation (LLPS) underlies the formation of intracellular membraneless
compartments in biology and may have played a role in the formation of protocells that …

PhaSepDB in 2022: annotating phase separation-related proteins with droplet states, co-phase separation partners and other experimental information

C Hou, X Wang, H **e, T Chen, P Zhu… - Nucleic Acids …, 2023 - academic.oup.com
Phase separation (PS) proteins form droplets to regulate myriad membraneless organelles
(MLOs) and cellular pathways such as transcription, signaling transduction and protein …

Achieving Environmentally‐Adaptive and Multifunctional Hydrodynamic Metamaterials through Active Control

C Jiang, H Nie, M Chen, X Shen, L Xu - Advanced Materials, 2025 - Wiley Online Library
As hydrodynamic metamaterials continue to develop, the inherent limitations of passive‐
mode metamaterials become increasingly apparent. First, passive devices are typically …

Membraneless organelles in health and disease: exploring the molecular basis, physiological roles and pathological implications

Y Li, Y Liu, XY Yu, Y Xu, X Pan, Y Sun… - … and Targeted Therapy, 2024 - nature.com
Once considered unconventional cellular structures, membraneless organelles (MLOs),
cellular substructures involved in biological processes or pathways under physiological …

CD-CODE: crowdsourcing condensate database and encyclopedia

N Rostam, S Ghosh, CFW Chow, A Hadarovich… - Nature …, 2023 - nature.com
The discovery of biomolecular condensates transformed our understanding of intracellular
compartmentalization of molecules. To integrate interdisciplinary scientific knowledge about …