It is likely that nanofabrication will underpin many technologies in the 21st century. Synthetic
chemistry is a powerful approach to generate molecular structures that are capable of …

The high affinity and specificity of peptides towards biological targets, in addition to their
favorable pharmacological properties, has encouraged the development of many peptide …

The construction of bioactive peptides using β-amino acid-containing sequence patterns is a
very promising strategy to obtain analogues that exhibit properties of high interest for …

The functions performed by proteins and nucleic acids provide the foundation for life.
Chemists have recently begun to ask whether it is possible to design synthetic oligomers …

The programmed synthesis of sequence-defined biomaterials whose monomer backbones
diverge from those of canonical α-amino acids represents the next frontier in protein and …

The principal secondary structural motifs adopted by peptides assembled from β‐amino acid
units are discussed: the 14‐, 12‐, 10‐, 12/10‐, and 8‐helices, as well as the hairpin turn …

Due to their unique characteristics, which are not shared by canonical α-peptides, peptides
that contain stretches of consecutive β-amino acids are attractive scaffolds for novel peptide …

It has recently been reported that ribosomes from erythromycin-resistant Escherichia coli
strains, when isolated in S30 extracts and incubated with chemically mis-acylated tRNA, can …

Host-defense peptides inhibit bacterial growth but manifest relatively little toxicity toward
eukaryotic cells. Many host-defense peptides adopt α-helical conformations in which …

The rational design of α-helix–mimicking peptidomimetics provides a streamlined approach
to discover potent inhibitors for protein− protein interactions (PPIs). However, designing cell …