Genomic selection in plant breeding: methods, models, and perspectives
Genomic selection (GS) facilitates the rapid selection of superior genotypes and accelerates
the breeding cycle. In this review, we discuss the history, principles, and basis of GS and …
the breeding cycle. In this review, we discuss the history, principles, and basis of GS and …
Smart breeding driven by big data, artificial intelligence, and integrated genomic-enviromic prediction
The first paradigm of plant breeding involves direct selection-based phenotypic observation,
followed by predictive breeding using statistical models for quantitative traits constructed …
followed by predictive breeding using statistical models for quantitative traits constructed …
Computationally efficient whole-genome regression for quantitative and binary traits
Genome-wide association analysis of cohorts with thousands of phenotypes is
computationally expensive, particularly when accounting for sample relatedness or …
computationally expensive, particularly when accounting for sample relatedness or …
Efficient Bayesian mixed-model analysis increases association power in large cohorts
Linear mixed models are a powerful statistical tool for identifying genetic associations and
avoiding confounding. However, existing methods are computationally intractable in large …
avoiding confounding. However, existing methods are computationally intractable in large …
Genome-wide regression and prediction with the BGLR statistical package
Many modern genomic data analyses require implementing regressions where the number
of parameters (p, eg, the number of marker effects) exceeds sample size (n). Implementing …
of parameters (p, eg, the number of marker effects) exceeds sample size (n). Implementing …
Genomic prediction of (mal) adaptation across current and future climatic landscapes
Signals of local adaptation have been found in many plants and animals, highlighting the
heterogeneity in the distribution of adaptive genetic variation throughout species ranges. In …
heterogeneity in the distribution of adaptive genetic variation throughout species ranges. In …
Polygenic modeling with Bayesian sparse linear mixed models
Both linear mixed models (LMMs) and sparse regression models are widely used in
genetics applications, including, recently, polygenic modeling in genome-wide association …
genetics applications, including, recently, polygenic modeling in genome-wide association …
Pitfalls of predicting complex traits from SNPs
The success of genome-wide association studies (GWASs) has led to increasing interest in
making predictions of complex trait phenotypes, including disease, from genotype data …
making predictions of complex trait phenotypes, including disease, from genotype data …
Genomic selection: genome-wide prediction in plant improvement
Association analysis is used to measure relations between markers and quantitative trait loci
(QTL). Their estimation ignores genes with small effects that trigger underpinning …
(QTL). Their estimation ignores genes with small effects that trigger underpinning …
Impacts of salinity stress on crop plants: Improving salt tolerance through genetic and molecular dissection
Improper use of water resources in irrigation that contain a significant amount of salts, faulty
agronomic practices such as improper fertilization, climate change etc. are gradually …
agronomic practices such as improper fertilization, climate change etc. are gradually …