[HTML][HTML] Endometriosis-associated infertility: From pathophysiology to tailored treatment

G Bonavina, HS Taylor - Frontiers in endocrinology, 2022 - frontiersin.org
Despite the clinically recognized association between endometriosis and infertility, the
mechanisms implicated in endometriosis-associated infertility are not fully understood …

The pathogenesis of endometriosis: molecular and cell biology insights

AS Laganà, S Garzon, M Götte, P Viganò… - International journal of …, 2019 - mdpi.com
The etiopathogenesis of endometriosis is a multifactorial process resulting in a
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …

Diagnosis of endometriosis in the 21st century

L Kiesel, M Sourouni - Climacteric, 2019 - Taylor & Francis
Endometriosis is a common disease but, due to the wide spectrum of symptoms, diagnosis
can be delayed 8–12 years. Laparoscopy is nowadays the gold standard for diagnosis. A …

MicroRNAs in endometriosis: biological function and emerging biomarker candidates

S Bjorkman, HS Taylor - Biology of Reproduction, 2019 - academic.oup.com
MicroRNAs (miRNAs), a class of small noncoding RNA molecules, have been recognized as
key post-transcriptional regulators associated with a multitude of human diseases. Global …

[HTML][HTML] An update on the multifaceted role of NF-kappaB in endometriosis

Y Liu, J Wang, X Zhang - International journal of biological …, 2022 - ncbi.nlm.nih.gov
Endometriosis remains a common but challenging gynecological disease among
reproductive-aged women with an unclear pathogenesis and limited therapeutic options …

Single-cell transcriptomic analysis of endometriosis provides insights into fibroblast fates and immune cell heterogeneity

J Ma, L Zhang, H Zhan, Y Mo, Z Ren, A Shao, J Lin - Cell & Bioscience, 2021 - Springer
Background Endometriosis is an oestrogen-dependent disease with an unclear aetiology
and pathogenesis affecting 6–10% of the global female population, predominantly those of …

A lifelong impact on endometriosis: pathophysiology and pharmacological treatment

LH Chen, WC Lo, HY Huang, HM Wu - International Journal of Molecular …, 2023 - mdpi.com
Endometriosis is a chronic inflammatory disease associated with bothersome symptoms in
premenopausal women and is complicated with long-term systemic impacts in the post …

Non-coding RNAs in endometrial physiopathology

A La Ferlita, R Battaglia, F Andronico, S Caruso… - International journal of …, 2018 - mdpi.com
The Human Genome Project led to the discovery that about 80% of our DNA is transcribed in
RNA molecules. Only 2% of the human genome is translated into proteins, the rest mostly …

[HTML][HTML] miR-484 mediates oxidative stress-induced ovarian dysfunction and promotes granulosa cell apoptosis via SESN2 downregulation

X Wang, J Yang, H Li, H Mu, L Zeng, S Cai, P Su, H Li… - Redox Biology, 2023 - Elsevier
Ovarian dysfunction is a common cause of female infertility, which is associated with genetic,
autoimmune and environmental factors. Granulosa cells (GCs) constitute the largest cell …

Genetic, epigenetic, and steroidogenic modulation mechanisms in endometriosis

A Zubrzycka, M Zubrzycki, E Perdas… - Journal of clinical …, 2020 - mdpi.com
Endometriosis is a chronic gynecological disease, affecting up to 10% of reproductive-age
women. The exact cause of the disease is unknown; however, it is a heritable condition …