PII proteins are multitasking information-processing proteins occurring in bacteria, archaea,
and plastids, decoding the metabolic state of the cells and providing this information to …

Ongoing social, political and ecological changes in the 21st century have placed more
people at risk of life-threatening acute and chronic infections than ever before. The …

Abstract The Biological General Repository for Interaction Datasets (BioGRID:
https://thebiogrid. org) is an open access database dedicated to the curation and archival …

Residue-residue coevolution has been observed across a number of protein-protein
interfaces, but the extent of residue coevolution between protein families on the whole …

Increasing antibiotic resistance urges for new technologies for studying microbes and
antimicrobial mechanism of action. We adapted thermal proteome profiling (TPP) to probe …

Recent developments in high-throughput reverse genetics, have revolutionized our ability to
map gene function and interactions,,–. The power of these approaches depends on their …

We present the seventh report on the performance of methods for predicting the atomic
resolution structures of protein complexes offered as targets to the community‐wide initiative …

Serum antibodies can recognize both pathogens and commensal gut microbiota. However,
our current understanding of antibody repertoires is largely based on DNA sequencing of …

Sewage treatment plants (STPs) accumulate both antibiotic and nonantibiotic antimicrobial
compounds that can select for antibiotic resistant bacteria. Herein, we aimed to identify the …

Increasing numbers of protein interactions have been identified in high-throughput
experiments, but only a small proportion have solved structures. Recently, sequence …