[HTML][HTML] Boosting the full potential of PyMOL with structural biology plugins

S Rosignoli, A Paiardini - Biomolecules, 2022 - mdpi.com
Over the past few decades, the number of available structural bioinformatics pipelines,
libraries, plugins, web resources and software has increased exponentially and become …

Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein

J Lei, Y Kusov, R Hilgenfeld - Antiviral research, 2018 - Elsevier
The multi-domain non-structural protein 3 (Nsp3) is the largest protein encoded by the
coronavirus (CoV) genome, with an average molecular mass of about 200 kD. Nsp3 is an …

Neuropilin-1 is a host factor for SARS-CoV-2 infection

JL Daly, B Simonetti, K Klein, KE Chen, MK Williamson… - Science, 2020 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), uses the viral spike (S) protein for host cell …

DALI and the persistence of protein shape

L Holm - Protein Science, 2020 - Wiley Online Library
DALI is a popular resource for comparing protein structures. The software is based on
distance‐matrix alignment. The associated web server provides tools to navigate, integrate …

Targeting Magnaporthe oryzae effector MoErs1 and host papain-like protease OsRD21 interaction to combat rice blast

M Liu, F Wang, B He, J Hu, Y Dai, W Chen, M Yi… - Nature plants, 2024 - nature.com
Effector proteins secreted by plant pathogenic fungi are important artilleries against host
immunity, but there is no precedent of such effectors being explored as antifungal targets …

Discovery of potential multi-target-directed ligands by targeting host-specific SARS-CoV-2 structurally conserved main protease

RS Joshi, SS Jagdale, SB Bansode… - Journal of …, 2021 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in
the current COVID-19 pandemic. Worldwide this disease has infected over 2.5 million …

Structural specializations of the sperm tail

MR Leung, J Zeng, X Wang, MC Roelofs, W Huang… - Cell, 2023 - cell.com
Sperm motility is crucial to reproductive success in sexually reproducing organisms.
Impaired sperm movement causes male infertility, which is increasing globally. Sperm are …

Secreted pectin monooxygenases drive plant infection by pathogenic oomycetes

F Sabbadin, S Urresti, B Henrissat, AO Avrova… - Science, 2021 - science.org
The oomycete Phytophthora infestans is a damaging crop pathogen and a model organism
to study plant-pathogen interactions. We report the discovery of a family of copper …

Mirusviruses link herpesviruses to giant viruses

M Gaïa, L Meng, E Pelletier, P Forterre, C Vanni… - Nature, 2023 - nature.com
DNA viruses have a major influence on the ecology and evolution of cellular organisms,,–,
but their overall diversity and evolutionary trajectories remain elusive. Here we carried out a …

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

C Rogers, T Fernandes-Alnemri, L Mayes… - Nature …, 2017 - nature.com
Apoptosis is a genetically regulated cell suicide programme mediated by activation of the
effector caspases 3, 6 and 7. If apoptotic cells are not scavenged, they progress to a lytic and …