Diabetic kidney disease (DKD) is one of the fastest growing causes of chronic kidney
disease and associated morbidity and mortality. Preclinical research has demonstrated the …

Diabetes prevalence is increasing worldwide, especially through the increase of type 2
diabetes. Diabetic nephropathy occurs in up to 40% of diabetic patients and is the leading …

Diabetic nephropathy, a kidney complication arising from diabetes, is the leading cause of
death in diabetic patients. Unabated, the growing epidemic of diabetes is increasing …

Diabetic nephropathy is manifested in more than 10% of people with diabetes. It is a
common cause of kidney failure and end-stage kidney disease. Understanding of …

Inflammation is a key characteristic of kidney disease, but this immune response is two-
faced. In the acute phase of kidney injury, there is an activation of the immune cells to fight …

Diabetes mellitus represents a growing concern, both for public economy and global health.
In fact, it can lead to insidious macrovascular and microvascular complications, impacting …

Objective: Diabetic kidney disease (DKD) has become the major cause of end-stage renal
disease (ESRD) associated with the progression of renal fibrosis. As gut microbiota …

The prevalence of type 2 diabetes mellitus (T2DM) is increasing every year. Medications are
currently the most common therapy for T2DM. However, these medications have certain …

Pyroptosis is identified as a pro-inflammatory programmed cell death, mediated by
gasdermins (GSDMs) family of proteins accompanied by pro-inflammatory signals release …

Dysfunction of mesangial cells plays a significant role in the glomerular lesions and is
implicated in the pathophysiology of diabetic nephropathy (DN). Macrophages infiltration is …