Overview of Castleman disease

A Dispenzieri, DC Fajgenbaum - Blood, The Journal of the …, 2020 - ashpublications.org
Castleman disease (CD) describes a group of at least 4 disorders that share a spectrum of
characteristic histopathological features but have a wide range of etiologies, presentations …

HIV-associated cancers and lymphoproliferative disorders caused by Kaposi sarcoma herpesvirus and Epstein-Barr virus

KA Lurain, R Ramaswami, LT Krug… - Clinical Microbiology …, 2024 - journals.asm.org
Within weeks of the first report of acquired immunodeficiency syndrome (AIDS) in 1981, it
was observed that these patients often had Kaposi sarcoma (KS), a hitherto rarely seen skin …

Hematologic cancers in individuals infected by HIV

A Carbone, E Vaccher… - Blood, The Journal of the …, 2022 - ashpublications.org
HIV infection increases cancer risk and is linked to cancers associated to infectious agents
classified as carcinogenic to humans by the International Agency for Research on Cancer …

Modulators of the Hop-HSP90 protein–protein interaction disrupt KSHV lytic replication

MO Okpara, MC Vaaltyn, JL Watson… - ACS Infectious …, 2024 - ACS Publications
The central role of the chaperome in maintaining cellular proteostasis has seen numerous
viral families evolve to parasitically exploit host chaperones in their life cycle. The HSP90 …

Human herpesvirus 6, 7, and 8 in solid organ transplantation: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

R Pellett Madan, J Hand… - Clinical …, 2019 - Wiley Online Library
These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …

Clinical management of Kaposi sarcoma herpesvirus-associated diseases: an update on disease manifestations and treatment strategies

R Patel, K Lurain, R Yarchoan… - Expert review of anti …, 2023 - Taylor & Francis
Introduction Kaposi sarcoma herpes virus (KSHV) is associated with several diseases
including Kaposi sarcoma, a form of multicentric Castleman's disease, primary effusion …

Characteristics and outcomes of KSHV-associated multicentric Castleman disease with or without other KSHV diseases

R Ramaswami, K Lurain, MN Polizzotto… - Blood …, 2021 - ashpublications.org
Kaposi sarcoma (KS)-associated herpesvirus (KSHV)–associated multicentric Castleman
disease (MCD) is a relapsing and remitting systemic lymphoproliferative disorder …

Tocilizumab in patients with symptomatic Kaposi sarcoma herpesvirus–associated multicentric Castleman disease

R Ramaswami, K Lurain, CJ Peer… - Blood, The Journal …, 2020 - ashpublications.org
Background: Kaposi sarcoma herpesvirus (KSHV)-associated multicentric Castleman
disease (MCD) is a lymphoproliferative disorder driven by cytokine excess, particularly …

Malignancy and viral infections in Sub-Saharan Africa: A review

M Diakite, K Shaw-Saliba, CY Lau - Frontiers in Virology, 2023 - frontiersin.org
The burden of malignancy related to viral infection is increasing in Sub-Saharan Africa
(SSA). In 2018, approximately 2 million new cancer cases worldwide were attributable to …

Cancer Immunotherapy Trials Network 12: Pembrolizumab in HIV-Associated Kaposi Sarcoma

K Lurain, R Ramaswami, I Ekwede, V Eulo… - Journal of Clinical …, 2025 - ascopubs.org
PURPOSE Cancer Immunotherapy Trials Network 12 demonstrated safety of
pembrolizumab in treating advanced cancer in people with HIV. Here, we report results of …