Epigenetics in human obesity and type 2 diabetes
Epigenetic mechanisms control gene activity and the development of an organism. The
epigenome includes DNA methylation, histone modifications, and RNA-mediated processes …
epigenome includes DNA methylation, histone modifications, and RNA-mediated processes …
Physical exercise as an epigenetic modulator of brain plasticity and cognition
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …
function, the effects of which can last for considerable time. An emerging line of scientific …
Epigenetics of type 2 diabetes mellitus and weight change—a tool for precision medicine?
Pioneering studies performed over the past few decades demonstrate links between
epigenetics and type 2 diabetes mellitus (T2DM), the metabolic disorder with the most …
epigenetics and type 2 diabetes mellitus (T2DM), the metabolic disorder with the most …
[HTML][HTML] Sperm epigenetics and influence of environmental factors
Background Developmental programming of the embryo is controlled by genetic information
but also dictated by epigenetic information contained in spermatozoa. Lifestyle and …
but also dictated by epigenetic information contained in spermatozoa. Lifestyle and …
Exercise mimetics: harnessing the therapeutic effects of physical activity
Exercise mimetics are a proposed class of therapeutics that specifically mimic or enhance
the therapeutic effects of exercise. Increased physical activity has demonstrated positive …
the therapeutic effects of exercise. Increased physical activity has demonstrated positive …
Epigenetic mechanisms of transmission of metabolic disease across generations
VM Sales, AC Ferguson-Smith, ME Patti - Cell metabolism, 2017 - cell.com
Both human and animal studies indicate that environmental exposures experienced during
early life can robustly influence risk for adult disease. Moreover, environmental exposures …
early life can robustly influence risk for adult disease. Moreover, environmental exposures …
POHaD: why we should study future fathers
A Soubry - Environmental epigenetics, 2018 - academic.oup.com
The growing field of 'Developmental Origin of Health and Disease'(DOHaD) generally
reflects environmental influences from mother to child. The importance of maternal lifestyle …
reflects environmental influences from mother to child. The importance of maternal lifestyle …
Effects of maternal and paternal exercise on offspring metabolism
Maternal and paternal obesity and type 2 diabetes are recognized risk factors for the
development of metabolic dysfunction in offspring, even when the offspring follow a healthful …
development of metabolic dysfunction in offspring, even when the offspring follow a healthful …
The preconception environment and sperm epigenetics
Background Infertility is a common reproductive disorder, with male factor infertility
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …
Impact of parental exposure on offspring health in humans
The possibility that parental life experiences and environmental exposures influence mental
and physical health across generations is an important concept in biology and medicine …
and physical health across generations is an important concept in biology and medicine …