[HTML][HTML] Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review

G Muteeb, MT Rehman, M Shahwan, M Aatif - Pharmaceuticals, 2023‏ - mdpi.com
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

Urinary tract infections: the current scenario and future prospects

G Mancuso, A Midiri, E Gerace, M Marra, S Zummo… - Pathogens, 2023‏ - mdpi.com
Urinary tract infections (UTIs) are among the most common bacterial infections worldwide,
occurring in both community and healthcare settings. Although the clinical symptoms of UTIs …

[PDF][PDF] Drug allergy: a 2022 practice parameter update

DA Khan, A Banerji, KG Blumenthal, EJ Phillips… - Journal of Allergy and …, 2022‏ - Elsevier
Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …

Global threat of carbapenem-resistant gram-negative bacteria

SS Jean, D Harnod, PR Hsueh - Frontiers in cellular and infection …, 2022‏ - frontiersin.org
Infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-
negative bacteria (GNB), including carbapenem-resistant (CR) Enterobacterales (CRE; …

Antimicrobial stewardship: fighting antimicrobial resistance and protecting global public health

MAA Majumder, S Rahman, D Cohall… - Infection and drug …, 2020‏ - Taylor & Francis
Antimicrobial resistance (AMR) is a serious threat to global public health. It increases
morbidity and mortality, and is associated with high economic costs due to its health care …

Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: the PALACE randomized clinical trial

AM Copaescu, S Vogrin, F James… - JAMA internal …, 2023‏ - jamanetwork.com
Importance Fewer than 5% of patients labeled with a penicillin allergy are truly allergic. The
standard of care to remove the penicillin allergy label in adults is specialized testing …

Defining and combating antibiotic resistance from One Health and Global Health perspectives

S Hernando-Amado, TM Coque, F Baquero… - Nature …, 2019‏ - nature.com
Several interconnected human, animal and environmental habitats can contribute to the
emergence, evolution and spread of antibiotic resistance, and the health of these contiguous …

Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022‏ - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

Clinical practice guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2021 guideline on diagnosis and management …

CR Woods, JS Bradley, A Chatterjee… - Journal of the …, 2021‏ - academic.oup.com
This clinical practice guideline for the diagnosis and treatment of acute hematogenous
osteomyelitis (AHO) in children was developed by a multidisciplinary panel representing …

Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease

TA Blauwkamp, S Thair, MJ Rosen, L Blair… - Nature …, 2019‏ - nature.com
Thousands of pathogens are known to infect humans, but only a fraction are readily
identifiable using current diagnostic methods. Microbial cell-free DNA sequencing offers the …