[HTML][HTML] Antibacterial fatty acids: An update of possible mechanisms of action and implications in the development of the next-generation of antibacterial agents

G Casillas-Vargas, C Ocasio-Malavé, S Medina… - Progress in lipid …, 2021 - Elsevier
The antibacterial activity of fatty acids (FA) is well known in the literature and represents a
promising option for develo** the next-generation of antibacterial agents to treat a broad …

Antimicrobial resistance on farms: a review including biosecurity and the potential role of disinfectants in resistance selection

R Davies, A Wales - … reviews in food science and food safety, 2019 - Wiley Online Library
Resistance to therapeutic antimicrobial agents is recognized as a growing problem for both
human and veterinary medicine, and the need to address the issue in both of these linked …

Multitarget approaches against multiresistant superbugs

DA Gray, M Wenzel - ACS Infectious Diseases, 2020 - ACS Publications
Despite efforts to develop new antibiotics, antibacterial resistance still develops too fast for
drug discovery to keep pace. Often, resistance against a new drug develops even before it …

Strategies to combat antimicrobial resistance: anti-plasmid and plasmid curing

MMC Buckner, ML Ciusa… - FEMS microbiology …, 2018 - academic.oup.com
Antimicrobial resistance (AMR) is a global problem hindering treatment of bacterial
infections, rendering many aspects of modern medicine less effective. AMR genes (ARGs) …

Evolution of horizontal transmission in antimicrobial resistance plasmids

T Dimitriu - Microbiology, 2022 - microbiologyresearch.org
Mobile genetic elements (MGEs) are one of the main vectors for the spread of antimicrobial
resistance (AMR) across bacteria, due to their ability to move horizontally between bacterial …

The quest for novel antimicrobial compounds: emerging trends in research, development, and technologies

PK Mantravadi, KA Kalesh, RCJ Dobson, AO Hudson… - Antibiotics, 2019 - mdpi.com
Pathogenic antibiotic resistant bacteria pose one of the most important health challenges of
the 21st century. The overuse and abuse of antibiotics coupled with the natural evolutionary …

Pharmaceutical approaches to target antibiotic resistance mechanisms

D Schillaci, V Spanò, B Parrino… - Journal of medicinal …, 2017 - ACS Publications
There is urgent need for new therapeutic strategies to fight the global threat of antibiotic
resistance. The focus of this Perspective is on chemical agents that target the most common …

Incorporation of antibiotics into solid lipid nanoparticles: a promising approach to reduce antibiotic resistance emergence

L Arana, L Gallego, I Alkorta - Nanomaterials, 2021 - mdpi.com
Antimicrobial resistance is one of the biggest threats to global health as current antibiotics
are becoming useless against resistant infectious pathogens. Consequently, new …

Correlation between exogenous compounds and the horizontal transfer of plasmid-borne antibiotic resistance genes

Y Liu, Z Tong, J Shi, Y Jia, K Yang, Z Wang - Microorganisms, 2020 - mdpi.com
The global spread of antibiotic resistance has posed a serious threat to public healthcare
and undermined decades of progress made in the fight against bacterial infections. It has …

Inhibiting conjugation as a tool in the fight against antibiotic resistance

FE Graf, M Palm, J Warringer… - Drug development …, 2019 - Wiley Online Library
Antibiotic resistance, especially in gram‐negative bacteria, is spreading globally and rapidly.
Development of new antibiotics lags behind; therefore, novel approaches to the problem of …