Mitochondria are cellular organelles responsible for generation of chemical energy in the
process called oxidative phosphorylation. They originate from a bacterial ancestor and …

Coronaviruses represent a large family of enveloped RNA viruses that infect a large
spectrum of animals. In humans, the severe acute respiratory syndrome coronavirus type 2 …

Eukaryotic ribosome and cap-dependent translation are attractive targets in the antitumor,
antiviral, anti-inflammatory, and antiparasitic therapies. Currently, a broad array of small …

The human 80S ribosome is the cellular nucleoprotein nanomachine in charge of protein
synthesis that is profoundly affected during cancer transformation by oncogenic proteins and …

The knowledge about non-coding RNAs (ncRNAs) is rapidly increasing with new data
continuously emerging, regarding their diverse types, applications, and roles. Particular …

Protein synthesis is central to life and requires the ribosome, which catalyzes the stepwise
addition of amino acids to a polypeptide chain by undergoing a sequence of structural …

Although reported in the literature, ribosome heterogeneity is a phenomenon whose extent
and implications in cell and organismal biology is not fully appreciated. This has been the …

Mitochondria are the powerhouses of the cell as they produce the majority of ATP with their
oxidative phosphorylation (OXPHOS) machinery. The OXPHOS system is composed of the …

Viruses are obligate intracellular parasites that depend on the host's protein synthesis
machinery for translating their mRNAs. The viral mRNA (vRNA) competes with the host …

The spirochete bacterial pathogen Borrelia (Borreliella) burgdorferi (Bbu) affects more than
10% of the world population and causes Lyme disease in about half a million people in the …