Developmental periods such as gestation and adolescence have enhanced plasticity
leaving the brain vulnerable to harmful effects from nicotine use. Proper brain maturation …

Adolescence encompasses a sensitive developmental period of enhanced clinical
vulnerability to nicotine, tobacco, and e‐cigarettes. While there are sociocultural influences …

Adolescence is a time of major plasticity of brain systems that regulate motivated behavior
and cognition, and is also the age of peak onset of nicotine use. Although there has been a …

Nicotinic acetylcholine receptors (nAChRs) regulate critical aspects of brain maturation
during the prenatal, early postnatal, and adolescent periods. During these developmental …

Smoking is a leading cause of mortality and morbidity worldwide. Smoking initiation often
occurs during adolescence. This paper reviews and synthesizes adolescent development …

Background and rationale Epidemiological evidence suggests that people who begin
experimenting with drugs of abuse during early adolescence are more likely to develop …

This study compared the rewarding and aversive effects of nicotine in adolescent, adult, and
adult rats pre-exposed to nicotine during adolescence. Prior to conditioning, the rats were …

Background: Animal models are critical to improve our understanding of the neuronal
mechanisms underlying nicotine withdrawal. Nicotine dependence in rodents can be …

Previous studies have shown an association between cigarette use and altered resting-state
functional connectivity (rsFC) in many large-scale networks, sometimes complemented by …

Introduction The objective of this study was to examine age-, hormone-, and sex-dependent
differences to the behavioral effects of nicotine using place-conditioning procedures in …