Neurological complications have emerged as a significant cause of morbidity and mortality
in the ongoing COVID-19 pandemic. Beside respiratory insufficiency, many hospitalized …

Background Delirium is the most common neuropsychiatric syndrome encountered by
clinicians dealing with older adults and the medically ill and is best characterized by 5 core …

Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design:

Deep learning takes advantage of large datasets and computationally efficient training
algorithms to outperform other approaches at various machine learning tasks. However …

The blood-brain barrier (BBB) plays a key role in maintaining the specialized
microenvironment of the central nervous system (CNS), and enabling communication with …

Objectives To determine the relation between delirium in critically ill patients and their
outcomes in the short term (in the intensive care unit and in hospital) and after discharge …

Delirium is the most common neuropsychiatric syndrome found in the acute care setting,
with a prevalence ranging from 10% in general medicine to 85% in advanced cancer and …

Objective: Although numerous risk factors for delirium in the ICU have been proposed, the
strength of evidence supporting each risk factor remains unclear. This study systematically …

In 2010, under the guidance of the DGAI (German Society of Anaesthesiology and Intensive
Care Medicine) and DIVI (German Interdisciplinary Association for Intensive Care and …

Sleep is an important physiologic process, and lack of sleep is associated with a host of
adverse outcomes. Basic and clinical research has documented the important role circadian …