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Knowns and unknowns about the neurobiology of stuttering
Stuttering occurs in early childhood during a dynamic phase of brain and behavioral
development. The latest studies examining children at ages close to this critical …
development. The latest studies examining children at ages close to this critical …
Genetic testing in neurodevelopmental disorders
Neurodevelopmental disorders are the most prevalent chronic medical conditions
encountered in pediatric primary care. In addition to identifying appropriate descriptive …
encountered in pediatric primary care. In addition to identifying appropriate descriptive …
[HTML][HTML] Genetic control of expression and splicing in develo** human brain informs disease mechanisms
RL Walker, G Ramaswami, C Hartl, N Mancuso… - Cell, 2019 - cell.com
Tissue-specific regulatory regions harbor substantial genetic risk for disease. Because brain
development is a critical epoch for neuropsychiatric disease susceptibility, we characterized …
development is a critical epoch for neuropsychiatric disease susceptibility, we characterized …
Elephants as an animal model for self-domestication
L Raviv, SL Jacobson, JM Plotnik, J Bowman… - Proceedings of the …, 2023 - pnas.org
Humans are unique in their sophisticated culture and societal structures, their complex
languages, and their extensive tool use. According to the human self-domestication …
languages, and their extensive tool use. According to the human self-domestication …
Genetic architecture of childhood speech disorder: a review
AT Morgan, DJ Amor, MD St John, IE Scheffer… - Molecular …, 2024 - nature.com
Severe speech disorders lead to poor literacy, reduced academic attainment and negative
psychosocial outcomes. As early as the 1950s, the familial nature of speech disorders was …
psychosocial outcomes. As early as the 1950s, the familial nature of speech disorders was …
The genetic and molecular basis of developmental language disorder: A review
HS Mountford, R Braden, DF Newbury, AT Morgan - Children, 2022 - mdpi.com
Language disorders are highly heritable and are influenced by complex interactions
between genetic and environmental factors. Despite more than twenty years of research, we …
between genetic and environmental factors. Despite more than twenty years of research, we …
Severe childhood speech disorder: Gene discovery highlights transcriptional dysregulation
MS Hildebrand, VE Jackson, TS Scerri, O Van Reyk… - Neurology, 2020 - neurology.org
Objective Determining the genetic basis of speech disorders provides insight into the
neurobiology of human communication. Despite intensive investigation over the past 2 …
neurobiology of human communication. Despite intensive investigation over the past 2 …
Genetic aetiologies for childhood speech disorder: novel pathways co-expressed during brain development
A Kaspi, MS Hildebrand, VE Jackson, R Braden… - Molecular …, 2023 - nature.com
Childhood apraxia of speech (CAS), the prototypic severe childhood speech disorder, is
characterized by motor programming and planning deficits. Genetic factors make …
characterized by motor programming and planning deficits. Genetic factors make …
Estimates of the prevalence of motor speech disorders in children with idiopathic speech delay
LD Shriberg, J Kwiatkowski… - Clinical linguistics & …, 2019 - Taylor & Francis
The goal of this research was to obtain initial estimates of the prevalence of each of four
types of motor speech disorders in children with idiopathic Speech Delay (SD) and to use …
types of motor speech disorders in children with idiopathic Speech Delay (SD) and to use …
Recapitulation and reversal of schizophrenia-related phenotypes in Setd1a-deficient mice
J Mukai, E Cannavò, GW Crabtree, Z Sun… - Neuron, 2019 - cell.com
SETD1A, a lysine-methyltransferase, is a key schizophrenia susceptibility gene. Mice
carrying a heterozygous loss-of-function mutation of the orthologous gene exhibit alterations …
carrying a heterozygous loss-of-function mutation of the orthologous gene exhibit alterations …