CRISPR technology: A decade of genome editing is only the beginning

JY Wang, JA Doudna - Science, 2023‏ - science.org
The advent of clustered regularly interspaced short palindromic repeat (CRISPR) genome
editing, coupled with advances in computing and imaging capabilities, has initiated a new …

End-to-end design of wearable sensors

HC Ates, PQ Nguyen, L Gonzalez-Macia… - Nature Reviews …, 2022‏ - nature.com
Wearable devices provide an alternative pathway to clinical diagnostics by exploiting
various physical, chemical and biological sensors to mine physiological (biophysical and/or …

Past, present, and future of CRISPR genome editing technologies

M Pacesa, O Pelea, M **ek - Cell, 2024‏ - cell.com
Genome editing has been a transformative force in the life sciences and human medicine,
offering unprecedented opportunities to dissect complex biological processes and treat the …

A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs

H Yan, Y Wen, Z Tian, N Hart, S Han… - Nature biomedical …, 2023‏ - nature.com
The use of microRNAs as clinical cancer biomarkers is hindered by the absence of accurate,
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …

Enabled efficient ammonia synthesis and energy supply in a zinc–nitrate battery system by separating nitrate reduction process into two stages

H Jiang, GF Chen, O Savateev, J Xue… - Angewandte Chemie …, 2023‏ - Wiley Online Library
The aqueous electrocatalytic reduction of NO3− into NH3 (NitrRR) presents a sustainable
route applicable to NH3 production and potentially energy storage. However, the NitrRR …

Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives

H Li, Y **e, F Chen, H Bai, L **u, X Zhou… - Chemical Society …, 2023‏ - pubs.rsc.org
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …

A CRISPR/Cas12a-empowered surface plasmon resonance platform for rapid and specific diagnosis of the Omicron variant of SARS-CoV-2

Z Chen, J Li, T Li, T Fan, C Meng, C Li… - National Science …, 2022‏ - academic.oup.com
The outbreak of the COVID-19 pandemic was partially due to the challenge of identifying
asymptomatic and presymptomatic carriers of the virus, and thus highlights a strong …

CRISPR in cancer biology and therapy

A Katti, BJ Diaz, CM Caragine, NE Sanjana… - Nature Reviews …, 2022‏ - nature.com
Over the past decade, CRISPR has become as much a verb as it is an acronym,
transforming biomedical research and providing entirely new approaches for dissecting all …

Coordination symmetry breaking of single‐atom catalysts for robust and efficient nitrate electroreduction to ammonia

XF Cheng, JH He, HQ Ji, HY Zhang, Q Cao… - Advanced …, 2022‏ - Wiley Online Library
Nitrate electrocatalytic reduction (NO3RR) for ammonia production is a promising strategy to
close the N‐cycle from nitration contamination, as well as an alternative to the Haber–Bosch …

Structurally Disordered RuO2 Nanosheets with Rich Oxygen Vacancies for Enhanced Nitrate Electroreduction to Ammonia

Y Wang, H Li, W Zhou, X Zhang, B Zhang… - Angewandte …, 2022‏ - Wiley Online Library
Electrochemical reduction of nitrate pollutants to ammonia has emerged as an attractive
alternative for ammonia synthesis. Currently, many strategies have been developed for …