Unlike traditional video games developed solely for entertainment purposes, game-based
learning employs intentionally crafted approaches that seamlessly merge entertainment and …

Molecular interaction networks lay the foundation for studying how biological functions are
controlled by the complex interplay of genes and proteins. Investigating perturbed processes …

Macrophages play an essential role in rheumatoid arthritis. Depending on their phenotype
(M1 or M2), they can play a role in the initiation or resolution of inflammation. The M1/M2 …

Rheumatoid arthritis (RA) is a complex autoimmune disease with an unknown aetiology.
However, rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) play a significant role in …

Computational modeling has emerged as a critical tool in investigating the complex
molecular processes involved in biological systems and diseases. In this study, we apply …

We describe a strategy for the development of a rational approach of neoplastic disease
therapy based on the demonstration that scale-free networks are susceptible to specific …

Dendritic cells (DCs) are professional antigen-presenting cells (APCs) with the unique ability
to mediate inflammatory responses of the immune system. Given the critical role of DCs in …

Cancer-associated fibroblasts (CAFs) are amongst the key players of the tumor
microenvironment (TME) and are involved in cancer initiation, progression, and resistance to …

In this work, we introduce Boolformer, the first Transformer architecture trained to perform
end-to-end symbolic regression of Boolean functions. First, we show that it can predict …

Interacting biological systems at all organizational levels display emergent behavior.
Modeling these systems is made challenging by the number and variety of biological …