Advances in proteomics have greatly improved chemical toxicity assessment and
predictions of adverse outcomes in organisms. Ecotoxicoproteomics has been employed to …

The merging of physiology and toxicokinetics, or pharmacokinetics, with computational
modeling to characterize dosimetry has led to major advances for both the chemical and …

Discontinuation of amitriptyline (AMI) has been demonstrated to induce long-term
withdrawal syndromes in mammals. However, no studies have focused on the persistent …

Background: Phthalates may disturb metabolic homeostasis in the liver by interfering with
the peroxisome proliferator-activated receptors (PPARs). However, the role of hepatic …

Background Organic food (OF) consumption has substantially increased in high income
countries, mostly driven by environmental concerns and health beliefs. Lower exposure to …

Pesticides are used in agricultural production worldwide, resulting in widespread
environmental pollution. Many diseases are closely related to exposure to pesticide …

Cetylpyridinium chloride (CPC) is a cationic surfactant that has been widely used as an
antibacterial ingredient in pharmaceutical and personal care products. Due to its high …

Chronic exposure to heavy metals such as Pb, As, and MeHg can be associated with an
increased risk of develo** neurodegenerative diseases. Our in vitro bioassays results …

Abstract Di-(2-ethylhexyl) phthalate (DEHP), one of the most common plasticizers, is closely
associated with a high prevalence of pubertal type 2 diabetes mellitus (T2DM). Numerous …

PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that are highly
expressed and extensively studied from the germline. piRNAs associate with PIWI proteins …