Pathophysiology, clinical presentation, and treatment of psoriasis: a review
Importance Approximately 125 million people worldwide have psoriasis. Patients with
psoriasis experience substantial morbidity and increased rates of inflammatory arthritis …
psoriasis experience substantial morbidity and increased rates of inflammatory arthritis …
2018 American College of Rheumatology/National Psoriasis Foundation guideline for the treatment of psoriatic arthritis
Objective: To develop an evidence-based guideline for the pharmacologic and
nonpharmacologic treatment of psoriatic arthritis (PsA), as a collaboration between the …
nonpharmacologic treatment of psoriatic arthritis (PsA), as a collaboration between the …
Secukinumab in plaque psoriasis—results of two phase 3 trials
RG Langley, BE Elewski, M Lebwohl… - … England Journal of …, 2014 - Mass Medical Soc
Background Interleukin-17A is considered to be central to the pathogenesis of psoriasis. We
evaluated secukinumab, a fully human anti–interleukin-17A monoclonal antibody, in …
evaluated secukinumab, a fully human anti–interleukin-17A monoclonal antibody, in …
Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics
Psoriasis is a chronic, inflammatory multisystem disease that affects up to 3.2% of the US
population. This guideline addresses important clinical questions that arise in psoriasis …
population. This guideline addresses important clinical questions that arise in psoriasis …
[HTML][HTML] Pathophysiology of atopic dermatitis: Clinical implications
J Kim, BE Kim, DYM Leung - Allergy and asthma proceedings, 2019 - ncbi.nlm.nih.gov
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. Genetic
predisposition, epidermal barrier disruption, and dysregulation of the immune system are …
predisposition, epidermal barrier disruption, and dysregulation of the immune system are …
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta‐analysis
E Sbidian, A Chaimani, R Guelimi… - Cochrane Database …, 2023 - cochranelibrary.com
Background Psoriasis is an immune‐mediated disease with either skin or joints
manifestations, or both, and it has a major impact on quality of life. Although there is …
manifestations, or both, and it has a major impact on quality of life. Although there is …
European S1 guideline for the treatment of hidradenitis suppurativa/acne inversa
Hidradenitis suppurativa/acne inversa (HS) is a chronic, inflammatory, recurrent, debilitating
skin disease of the hair follicle that usually presents after puberty with painful, deep‐seated …
skin disease of the hair follicle that usually presents after puberty with painful, deep‐seated …
Prevalence of psoriatic arthritis in patients with psoriasis: a systematic review and meta-analysis of observational and clinical studies
F Alinaghi, M Calov, LE Kristensen… - Journal of the American …, 2019 - Elsevier
Background Wide-ranging prevalence estimates of psoriatic arthritis (PsA) in patients with
psoriasis have been reported. Objectives To assess the prevalence and incidence of PsA in …
psoriasis have been reported. Objectives To assess the prevalence and incidence of PsA in …
Innate IL-17-producing cells: the sentinels of the immune system
Abstract The cytokine interleukin-17 (IL-17) has received considerable attention since the
discovery of a distinct CD4+ T helper (TH) cell subset that produces it, known as the TH17 …
discovery of a distinct CD4+ T helper (TH) cell subset that produces it, known as the TH17 …
Th17 cells and the IL-23/IL-17 axis in the pathogenesis of periodontitis and immune-mediated inflammatory diseases
K Bunte, T Beikler - International journal of molecular sciences, 2019 - mdpi.com
Innate immunity represents the semi-specific first line of defense and provides the initial host
response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive …
response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive …