Cell wall thickness and the molecular mechanism of heterogeneous vancomycin‐intermediate Staphylococcus aureus

J Cui, H Zhang, Z Mo, M Yu… - Letters in applied …, 2021 - academic.oup.com
Methicillin‐resistant Staphylococcus aureus (MRSA) with reduced sensitivity to vancomycin
(VAN) has caused many clinical cases of VAN treatment failure, but the molecular …

Targeting cyclin-dependent kinase 11: a computational approach for natural anti-cancer compound discovery

S Bhambri, PC Jha - Molecular Diversity, 2025 - Springer
Cancer, a leading global cause of death, presents considerable treatment challenges due to
resistance to conventional therapies like chemotherapy and radiotherapy. Cyclin-dependent …

Synthesis and inhibitory activity against MurA and MurZ enzymes of 4 H-pyrano [2, 3-d] pyrimidine–1 H-1, 2, 3-triazole hybrid compounds having piperidine and …

DT Nguyen, SH Do, NT Vu, TK Van Hoang… - New Journal of …, 2023 - pubs.rsc.org
A series of D-glucose-conjugated 4H-pyrano [2, 3-d] pyrimidine–1H-1, 2, 3-triazole hybrid
compounds 12a–g and 13a–g having piperidine and morpholine rings were synthesized by …

Discovery of a Potential Molluscicide Based on Protein PcRoo in Gill Cilia of Pomacea canaliculata

C Yang, Y Ma, Y Wang, M Zhang… - Journal of Agricultural …, 2023 - ACS Publications
In modern pesticide discovery, target-based drug design is an attractive and cost-effective
approach. Previous studies found that protein rootletin (PcRoo) is a target protein of …

Exploring some marine-derived manzamine compounds for uterine fibroid treatment: molecular docking and dynamics studies

AOH Zayed - Discover Chemistry, 2025 - Springer
Women commonly experience uterine fibroids, which are benign tumors within the uterine
muscle characterized by irregular extracellular matrix deposition and abnormal smooth …