Podocytopathies

JB Kopp, HJ Anders, K Susztak, MA Podestà… - Nature reviews Disease …, 2020 - nature.com
Podocytopathies are kidney diseases in which direct or indirect podocyte injury drives
proteinuria or nephrotic syndrome. In children and young adults, genetic variants in> 50 …

[HTML][HTML] Sex and gender differences in chronic kidney disease and access to care around the globe

GG García, A Iyengar, F Kaze, C Kierans… - Seminars in …, 2022 - Elsevier
The difference between sex, the biological construct, and gender, the social construct, may
be most evident in settings of vulnerability. Globally, chronic kidney disease is more …

Membranous nephropathy

P Ronco, L Beck, H Debiec, FC Fervenza… - Nature reviews Disease …, 2021 - nature.com
Membranous nephropathy (MN) is a glomerular disease that can occur at all ages. In adults,
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …

A systematic literature review of the epidemiology, health-related quality of life impact, and economic burden of immunoglobulin A nephropathy

CS Kwon, P Daniele, A Forsythe… - Journal of Health …, 2021 - pmc.ncbi.nlm.nih.gov
Introduction: This systematic literature review analyzed published evidence on IgA
nephropathy (IgAN), focusing on US epidemiology, health-related quality of life (HRQoL) …

Identifying outcomes important to patients with glomerular disease and their caregivers

SA Carter, T Gutman, C Logeman… - Clinical Journal of the …, 2020 - journals.lww.com
Results Across 16 focus groups, 134 participants (range, 19–85 years old; 51% women),
including 101 patients and 33 caregivers, identified 58 outcomes. The ten highest-ranked …

The management of multi-morbidity in elderly patients: Ready yet for precision medicine in intensive care?

M Beil, H Flaatten, B Guidet, S Sviri, C Jung… - Critical Care, 2021 - Springer
There is ongoing demographic ageing and increasing longevity of the population, with
previously devastating and often-fatal diseases now transformed into chronic conditions …

Urgency and its association with quality of life and clinical outcomes in patients with ulcerative colitis

JA Sninsky, EL Barnes, X Zhang… - Official journal of the …, 2022 - journals.lww.com
METHODS: We conducted a cross-sectional and subsequent longitudinal study within
Inflammatory Bowel Disease Partners, a patient-powered research network. We described …

Idiopathic membranous nephropathy: glomerular pathological pattern caused by extrarenal immunity activity

W Liu, C Gao, Z Liu, H Dai, Z Feng, Z Dong… - Frontiers in …, 2020 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is a pathological pattern of glomerular damage
caused by an autoimmune response. Immune complex deposition, thickness of glomerular …

[HTML][HTML] Iptacopan in idiopathic immune complex–mediated membranoproliferative glomerulonephritis: protocol of the APPARENT multicenter, randomized phase 3 …

M Vivarelli, AS Bomback, M Meier, Y Wang… - Kidney international …, 2024 - Elsevier
Introduction Immune complex–mediated membranoproliferative glomerulonephritis (IC-
MPGN) is an ultra-rare, fast-progressing kidney disease that may be idiopathic (primary) or …

[HTML][HTML] Sex and gender in glomerular disease

H Beckwith, L Lightstone, S McAdoo - Seminars in Nephrology, 2022 - Elsevier
There is increasing understanding that a multifaceted interplay of sex-dependent genetic
and immune dysregulation underpins the development of glomerular disorders. Regional …