The vast majority of agricultural land undergoes abiotic stress that can significantly reduce
agricultural yields. Understanding the mechanisms of plant defenses against stresses and …

Deep Learning (DL) has recently enabled unprecedented advances in one of the grand
challenges in computational biology: the half-century-old problem of protein structure …

Much of the complexity within cells arises from functional and regulatory interactions among
proteins. The core of these interactions is increasingly known, but novel interactions …

Ferroptosis, a form of regulated cell death that is driven by iron-dependent phospholipid
peroxidation, has been implicated in multiple diseases, including cancer,–, degenerative …

Abstract Characterization of the genetic landscape of Alzheimer's disease (AD) and related
dementias (ADD) provides a unique opportunity for a better understanding of the associated …

Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a
disabling disorder, yet the clinical phenotype is poorly defined, the pathophysiology is …

IgA nephropathy (IgAN) is a progressive form of kidney disease defined by glomerular
deposition of IgA. Here we performed a genome-wide association study of 10,146 kidney …

Multiple sclerosis is a complex autoimmune disease, and several therapies for multiple
sclerosis have been developed and widely used. However, existing medications for multiple …

Inflammatory bowel diseases (IBDs) are chronic disorders of the gastrointestinal tract with
the following two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). To date, most …

The plasma proteome can help bridge the gap between the genome and diseases. Here we
describe genome-wide association studies (GWASs) of plasma protein levels measured with …