Major depressive disorder
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …
Candidate biomarkers in psychiatric disorders: state of the field
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …
aid in objectively diagnosing patients and providing individualized treatment …
The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders
Stress is a primary risk factor for several neuropsychiatric disorders. Evidence from
preclinical models and clinical studies of depression have revealed an array of structural …
preclinical models and clinical studies of depression have revealed an array of structural …
Gut-microbiome-expressed 3β-hydroxysteroid dehydrogenase degrades estradiol and is linked to depression in premenopausal females
D Li, T Sun, Y Tong, J Le, Q Yao, J Tao, H Liu, W Jiao… - Cell metabolism, 2023 - cell.com
Estradiol decline can result in depressive disorders in females; nevertheless, the causes of
this decline are unclear. In this study, we isolated estradiol-degrading Klebsiella aerogenes …
this decline are unclear. In this study, we isolated estradiol-degrading Klebsiella aerogenes …
3β-Hydroxysteroid dehydrogenase expressed by gut microbes degrades testosterone and is linked to depression in males
D Li, R Liu, M Wang, R Peng, S Fu, A Fu, J Le, Q Yao… - Cell host & …, 2022 - cell.com
Testosterone deficiency can lead to depressive symptoms in humans; however, the causes
of this deficiency are incompletely understood. Here, we isolated Mycobacterium neoaurum …
of this deficiency are incompletely understood. Here, we isolated Mycobacterium neoaurum …
Ginsenoside Rg1 in neurological diseases: From bench to bedside
S Yang, J Wang, P Cheng, L Chen, J Hu… - Acta Pharmacologica …, 2023 - nature.com
Ginseng has been used in China as a superior medicinal material for thousands of years
that can nourish the five internal organs, calm the mind and benefit wisdom. Due to its anti …
that can nourish the five internal organs, calm the mind and benefit wisdom. Due to its anti …
The HPA axis as target for depression
A Menke - Current Neuropharmacology, 2024 - benthamdirect.com
Major depressive disorder (MDD) is a stress-related mental disorder with a lifetime
prevalence of 20% and, thus, is one of the most prevalent mental health disorders …
prevalence of 20% and, thus, is one of the most prevalent mental health disorders …