Achieving 80% ten‐fold cross‐validated accuracy for secondary structure prediction by large‐scale training

O Dor, Y Zhou - Proteins: Structure, Function, and …, 2007 - Wiley Online Library
An integrated system of neural networks, called SPINE, is established and optimized for
predicting structural properties of proteins. SPINE is applied to three‐state secondary …

An integrated network topology and deep learning model for prediction of Alzheimer disease candidate genes

NS Gnanadesigan, N Dhanasegar, MD Ramasamy… - Soft Computing, 2023 - Springer
Alzheimer's disease (AD) is a neurological illness that causes short-term memory loss.
There are currently no viable therapeutic therapies for this condition that can cure it. The …

Prediction of protein folds: extraction of new features, dimensionality reduction, and fusion of heterogeneous classifiers

P Ghanty, NR Pal - IEEE transactions on nanobioscience, 2009 - ieeexplore.ieee.org
Here, we consider a two-level (four classes in level 1 and 27 folds in level 2) protein fold
determination problem. We propose several new features and use some existing features …

A balanced secondary structure predictor

MN Islam, S Iqbal, AR Katebi, MT Hoque - Journal of theoretical biology, 2016 - Elsevier
Secondary structure (SS) refers to the local spatial organization of a polypeptide backbone
atoms of a protein. Accurate prediction of SS can provide crucial features to form the next …

Learning sparse models for a dynamic Bayesian network classifier of protein secondary structure

Z Aydin, A Singh, J Bilmes, WS Noble - BMC bioinformatics, 2011 - Springer
Background Protein secondary structure prediction provides insight into protein function and
is a valuable preliminary step for predicting the 3D structure of a protein. Dynamic Bayesian …

[PDF][PDF] Protein structure prediction using support vector machine

AK Mandle, P Jain, SK Shrivastava - International Journal on Soft …, 2012 - academia.edu
ABSTRACT Support Vector Machine (SVM) is used for predict the protein structural.
Bioinformatics method use to protein structure prediction mostly depends on the amino acid …

A new hybrid coding for protein secondary structure prediction based on primary structure similarity

Z Li, J Wang, S Zhang, Q Zhang, W Wu - Gene, 2017 - Elsevier
The coding pattern of protein can greatly affect the prediction accuracy of protein secondary
structure. In this paper, a novel hybrid coding method based on the physicochemical …

Enhanced artificial neural network for protein fold recognition and structural class prediction

P Sudha, D Ramyachitra, P Manikandan - Gene Reports, 2018 - Elsevier
Abstract In Bioinformatics Protein Fold Recognition (PFR) and Structural Class Prediction
(SCP) is a significant problem in predicting protein with a three dimensional structure …

Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom

PM Watt, WR Thomas, R Hopkins - US Patent 7,803,765, 2010 - Google Patents
US7803765B2 - Methods of constructing biodiverse gene fragment libraries and biological
modulators isolated therefrom - Google Patents US7803765B2 - Methods of constructing …

Physicochemical feature-based classification of amino acid mutations

B Shen, J Bai, M Vihinen - Protein Engineering, Design & …, 2008 - academic.oup.com
A huge quantity of gene and protein sequences have become available during the post-
genomic era, and information about genetic variations, including amino acid substitutions …