Kinetic resolution, dynamic kinetic resolution and desymmetrization are practical methods to
produce enantioenriched products from relatively simple racemic or achiral starting …

As a type of readily available small strained-ring heterocycle, meso-aziridines may undergo
catalytic desymmetrizing transformations to empower the rapid construction of diverse …

Herein, we report the first example of a highly enantioselective alkylative aziridine ring
opening. Under the catalysis of a chiral nickel/pyridine-imidazoline complex, asymmetric C …

An efficient kinetic resolution of racemic trans-2, 3-aziridinyl alcohols is established via zinc
catalyzed ring opening reactions with various amines as the nucleophiles. The directing …

Chiral secondary alkyl amines with a vicinal quaternary stereocenter are undoubtedly
important and ubiquitous subunits in natural products and pharmaceuticals. However, their …

Catalytic kinetic resolution (KR) and dynamic kinetic asymmetric transformation (DyKAT) are
alternative and complementary avenues to access chiral stereoisomers of both starting …

We report a chiral phosphoric acid catalyzed apparent hydrolytic ring-opening reaction of
racemic aziridines in a regiodivergent parallel kinetic resolution manner. Harnessing the …

The oxirane and aziridine rings are valuable building blocks in modern synthetic chemistry
and catalytic asymmetric ring opening reactions of these three membered ring systems have …

Under the catalysis of a Cu (I) or Ag (I) salt with a chiral diphosphine ligand, the
enantioselective nucleophilic ring opening of racemic 2‐styrenylaziridines via kinetic …

The enantioselective [3+ 1]-cycloaddition of racemic donor–acceptor (D–A) aziridines with
isocyanides was first realized under mild reaction conditions using a chiral N, N …