Background: Acute kidney injury (AKI) is a common and potentially fatal complication
encountered during a variety of kidney surgeries. Renal ischemia/reperfusion (I/R) injury is …

Bipolar disorder's core feature is the pathological disturbances in mood, often accompanied
by disrupted thinking and behavior. Its complex and heterogeneous etiology implies that a …

Abstract Background Ischemia/reperfusion (I/R) is the predominant cause of acute renal
failure (ARF), which damages the remote organs, especially the heart, and subsequently …

This study aims to investigate the wound-healing effectiveness of the phenolic compound,
naringin, both in vitro and in vivo. Male mice were shaved on their dorsal skin under …

Sepsis is a potential fetal organ destruction brought on through an overzealous immunologic
reaction to infection, causing severe inflammation, septic shock, and damage to different …

Endothelial dysfunction is a hallmark of cardiovascular diseases, contributing to impaired
vasodilation, altered hemodynamics, and atherosclerosis progression. Trimetazidine …

Cisplatin nephrotoxicity is a well-known emergency clinical condition caused by oxidative
stress and inflammation. Naringin (NAR) is considered an antioxidant agent with …

Naringin is a natural flavonoid with therapeutic properties found in citrus fruits and an active
natural product from herbal plants. Naringin has become a focus of attention in recent years …

We aimed to evaluate the functions of long non-coding RNA taurine upregulated gene 1
(lncRNA TUG1) in renal ischemia-reperfusion (I/R) injury and identify the potential …

Objective Trimetazidine (TMZ) exerts a strong inhibitory effect on ischemia/reperfusion (I/R)
injury. Inflammation plays a key role in I/R injury. We hypothesized that TMZ may protect …