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Memory T cells: strategies for optimizing tumor immunotherapy
Q Liu, Z Sun, L Chen - Protein & cell, 2020 - academic.oup.com
Several studies have demonstrated that memory T cells including stem cell memory (Tscm)
T cells and central memory (Tcm) T cells show superior persistence and antitumor immunity …
T cells and central memory (Tcm) T cells show superior persistence and antitumor immunity …
Models, mechanisms and clinical evidence for cancer dormancy
JA Aguirre-Ghiso - Nature Reviews Cancer, 2007 - nature.com
Patients with cancer can develop recurrent metastatic disease with latency periods that
range from years even to decades. This pause can be explained by cancer dormancy, a …
range from years even to decades. This pause can be explained by cancer dormancy, a …
Metallo-alginate hydrogel can potentiate microwave tumor ablation for synergistic cancer treatment
Microwave ablation (MWA) as a local tumor ablation strategy suffers from posttreatment
tumor recurrence. Development of adjuvant biomaterials to potentiate MWA is therefore of …
tumor recurrence. Development of adjuvant biomaterials to potentiate MWA is therefore of …
Metronomic chemotherapy: new rationale for new directions
Tumor angiogenesis is recognized as a major therapeutic target in the fight against cancer.
The key involvement of angiogenesis in tumor growth and metastasis has started to redefine …
The key involvement of angiogenesis in tumor growth and metastasis has started to redefine …
Cancer micrometastases
Early spread of tumor cells is usually undetected by current imaging technologies. In
patients with cancer and no signs of overt metastases sensitive methods have been …
patients with cancer and no signs of overt metastases sensitive methods have been …
Dormant tumour cells, their niches and the influence of immunity
Despite increased focus on the clinical relevance of dormant metastatic disease, our
understanding of dormant niches, mechanisms underlying emergence from dormancy, and …
understanding of dormant niches, mechanisms underlying emergence from dormancy, and …
Immune-mediated dormancy: an equilibrium with cancer
MWL Teng, JB Swann, CM Koebel… - Journal of Leucocyte …, 2008 - academic.oup.com
This brief review discusses the role of the immune system in tumor development, covering a
history of cancer immunity and a summary of the concept of cancer immunoediting, including …
history of cancer immunity and a summary of the concept of cancer immunoediting, including …
[HTML][HTML] Decoding melanoma metastasis
WE Damsky Jr, LE Rosenbaum, M Bosenberg - Cancers, 2010 - mdpi.com
Metastasis accounts for the vast majority of morbidity and mortality associated with
melanoma. Evidence suggests melanoma has a predilection for metastasis to particular …
melanoma. Evidence suggests melanoma has a predilection for metastasis to particular …
ERK1/2 and p38α/β signaling in tumor cell quiescence: opportunities to control dormant residual disease
MS Sosa, A Avivar-Valderas, P Bragado… - Clinical cancer …, 2011 - aacrjournals.org
Systemic minimal residual disease after primary tumor treatment can remain asymptomatic
for decades. This is thought to be due to the presence of dormant disseminated tumor cells …
for decades. This is thought to be due to the presence of dormant disseminated tumor cells …
Metronomic cyclophosphamide treatment in metastasized breast cancer patients: immunological effects and clinical outcome
Y Ge, C Domschke, N Stoiber, S Schott, J Heil… - Cancer immunology …, 2012 - Springer
Severe immune suppression is frequent in late-stage tumor patients and promotes tumor
immune evasion and subsequent tumor progression. Regulatory T cells (Treg) are major …
immune evasion and subsequent tumor progression. Regulatory T cells (Treg) are major …