Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and
transcriptional modulators with crucial functions in hepatic and whole-body energy …

The concentration of biomolecules in living systems shows numerous systematic and
random variations. Systematic variations can be classified based on the frequency of …

Tissue sensitivity and response to exercise vary according to the time of day and alignment
of circadian clocks, but the optimal exercise time to elicit a desired metabolic outcome is not …

While the timing of food intake is important, it is unclear whether the effects of exercise on
energy metabolism are restricted to unique time windows. As circadian regulation is key to …

This is the first rigorous, self-contained treatment of the theory of deep learning. Starting with
the foundations of the theory and building it up, this is essential reading for any scientists …

The mammalian circadian clock, expressed throughout the brain and body, controls daily
metabolic homeostasis. Clock function in peripheral tissues is required, but not sufficient, for …

Objective The circadian clock aligns physiology with the 24-hour rotation of Earth. Light and
food are the main environmental cues (zeitgebers) regulating circadian rhythms in …

Myocardial ischemia-reperfusion (IR) injury is a severe rhythmic disease with a high
prevalence in the early morning. IR injury has a significant circadian rhythm in reactive …

The circadian clock is an endogenous, time-tracking system that directs multiple metabolic
and physiological functions required for homeostasis. The master or central clock located …

Life on Earth anticipates recurring 24-hour environmental cycles via genetically encoded
molecular clocks active in all mammalian organs. Communication between these clocks …