The main proteases (Mpro), also termed 3‐chymotrypsin‐like proteases (3CLpro), are a
class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has …

The disease severity of COVID-19, especially in the elderly and patients with co-morbidities,
is characterized by hypercytokinemia, an exaggerated immune response associated with an …

Despite the virulence and high fatality of coronavirus disease 2019 (COVID-19), no specific
antiviral treatment exists until the current moment. Natural agents with immune-promoting …

The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The …

The SARS-CoV-2 pandemic is considered as one of the most disastrous pandemics for
human health and the world economy. RNA-dependent RNA polymerase (RdRp) is one of …

At the end of 2019, a life threatening viral infection (COVID-19) caused by a novel
coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was …

Background: The world has been unprecedentedly hit by a global pandemic which broke the
record of deadly pandemics that faced humanity ever since its existence. Even kids are well …

Abstract Context Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is still ongoing and currently the most striking …

The coronavirus pandemic (SARS CoV-2) that has existed for over a year, constantly forces
scientists to search for drugs against this virus. In silico research and selected experimental …

The SARS-CoV-2 pandemic at the end of 2019 had major worldwide health and economic
consequences. Until effective vaccination approaches were created, the healthcare sectors …