Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …

The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to
the challenging field of virtual design and testing of technologies in a patient-specific …

Modeling the mechanical response of the brain has become increasingly important over the
past decades. Although mechanical stimuli to the brain are small under physiological …

This work formulates frictionless contact between solid bodies in terms of a repulsive
potential energy term and illustrates how numerical integration of the resulting forces is …

Alterations in brain rheology are increasingly recognized as a diagnostic marker for various
neurological conditions. Magnetic resonance elastography now allows us to assess brain …

The leaflets of the mitral valve interact with the mitral jet and significantly impact diastolic
flow patterns, but the effect of mitral valve morphology and kinematics on diastolic flow and …

Skin is a highly dynamic, autoregulated, living system that responds to mechanical stretch
through a net gain in skin surface area. Tissue expansion uses the concept of controlled …

Heart valves control unidirectional blood flow within the heart during the cardiac cycle. They
have a remarkable ability to withstand the demanding mechanical environment of the heart …

Computational modeling of thin biological membranes can aid the design of better medical
devices. Remarkable biological membranes include skin, alveoli, blood vessels, and heart …

As the first section of a multi-part review series, this section provides an overview of the
ongoing research and development aimed at fabricating novel heart valve replacements …