Vaccination is one of the most effective prophylactic public health interventions for the
prevention of infectious diseases such as coronavirus disease (COVID‐19). Considering the …

Although antibody escape is observed in emerging severe acute respiratory syndrome
coronavirus 2 variants, T cell escape, especially after the global circulation of BA. 2.86/JN. 1 …

Recognition of antigens by T cell receptors (TCRs) is a key component of adaptive immunity.
Understanding the structures of these TCR interactions provides major insights into immune …

Functional alterations with age are observed in all human systems, but the aging of the
adaptive immune system displays both general changes affecting all individuals, and …

T cell senescence alters the homeostasis of distinct T cell populations and results in
decayed adaptive immune protection in older individuals, but a link between aging and …

Identifying epitopes and their corresponding T-cell receptor (TCR) sequences is crucial in
the face of rapidly mutating viruses. Peptide synthesis is often required to confirm the exact …

The COVID-19 pandemic caused by the rapid spread of the novel coronavirus SARS-CoV-2,
has promoted an interest in studying the T-cell immune response. It was found that the …

The etiological agent for the coronavirus disease 2019 (COVID-19), the SARS-CoV-2,
caused a global pandemic. Although mRNA, viral-vectored, DNA, and recombinant protein …

Although emerging data have revealed the critical role of memory CD8+ T cells in
preventing and controlling SARS-CoV-2 infection, virus-specific CD8+ T-cell responses …